AIMC Topic: Double-Blind Method

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Promethazine for nausea and vomiting prevention after gynaecological laparoscopic surgery: A randomized controlled trial.

Scientific reports May 8, 2025
Postoperative nausea and vomiting (PONV) represent significant concerns for patients undergoing surgical procedures, as these symptoms greatly impact their postoperative experience. Among female patients undergoing laparoscopic surgery, the incidence...
Laparoscopy Young Adult Postoperative Nausea and Vomiting Metoclopramide Humans Antiemetics Adult Prospective Studies Gynecologic Surgical Procedures Middle Aged Female Promethazine Adolescent Aged Double-Blind Method
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Step up to triple therapy versus switch to dual bronchodilator therapy in patients with COPD on an inhaled corticosteroid/long-acting β-agonist: post-hoc analyses of KRONOS.

Respiratory research May 8, 2025
BACKGROUND: In people with chronic obstructive pulmonary disease (COPD) on inhaled corticosteroid/long-acting β-agonist (ICS/LABA) therapy, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommends stepping up to ICS/long-acting mu...
Drug Therapy, Combination Drug Substitution Muscarinic Antagonists Adrenal Cortex Hormones Administration, Inhalation Male Middle Aged Bronchodilator Agents Treatment Outcome Humans Adrenergic beta-2 Receptor Agonists Drug Combinations Female Double-Blind Method Aged Pulmonary Disease, Chronic Obstructive
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Towards conversational diagnostic artificial intelligence.

Nature Apr 9, 2025
At the heart of medicine lies physician-patient dialogue, where skillful history-taking enables effective diagnosis, management and enduring trust. Artificial intelligence (AI) systems capable of diagnostic dialogue could increase accessibility and q...
United Kingdom Physicians, Primary Care Medical History Taking Diagnosis Empathy Humans Artificial Intelligence Language Female Communication Male India Canada Double-Blind Method Physician-Patient Relations
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Structural and metabolic topological alterations associated with butylphthalide treatment in mild cognitive impairment: Data from a randomized, double-blind, placebo-controlled trial.

Psychiatry and clinical neurosciences Mar 31, 2025
AIMS: Effective intervention for mild cognitive impairment (MCI) is key for preventing dementia. As a neuroprotective agent, butylphthalide has the potential to treat MCI due to Alzheimer disease (AD). However, the pharmacological mechanism of butylp...
Humans Female Aged Aged, 80 and over Male Alzheimer Disease Positron-Emission Tomography Outcome Assessment, Health Care Nerve Net Benzofurans Middle Aged Cognitive Dysfunction Magnetic Resonance Imaging Neuroprotective Agents Double-Blind Method
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Neurorehabilitation in spinal cord injury: Increased cortical activity through tDCS and robotic gait training.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Mar 24, 2025
OBJECTIVE: This study investigates the neurophysiological outcomes of combining robot-assisted gait training (RAGT) with active transcranial direct current stimulation (tDCS) on individuals with spinal cord injury (SCI).
Humans Female Young Adult Adult Gait Male Spinal Cord Injuries Middle Aged Transcranial Direct Current Stimulation Spectroscopy, Near-Infrared Motor Cortex Robotics Neurological Rehabilitation Double-Blind Method
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Artificial intelligence for individualized treatment of persistent atrial fibrillation: a randomized controlled trial.

Nature medicine Feb 14, 2025
Although pulmonary vein isolation (PVI) has become the cornerstone ablation procedure for atrial fibrillation (AF), the optimal ablation procedure for persistent and long-standing persistent AF remains elusive. Targeting spatio-temporal electrogram d...
Precision Medicine Female Aged Male Middle Aged Humans Artificial Intelligence Algorithms Pulmonary Veins Treatment Outcome Double-Blind Method Anti-Arrhythmia Agents Atrial Fibrillation Catheter Ablation
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Transcutaneous spinal cord stimulation combined with robotic-assisted body weight-supported treadmill training enhances motor score and gait recovery in incomplete spinal cord injury: a double-blind randomized controlled clinical trial.

Journal of neuroengineering and rehabilitation Jan 30, 2025
BACKGROUND: Although transcutaneous spinal cord stimulation (tSCS) has been suggested as a safe and feasible intervention for gait rehabilitation, no studies have determined its effectiveness compared to sham stimulation.
Transcutaneous Electric Nerve Stimulation Spinal Cord Stimulation Middle Aged Treatment Outcome Muscle Strength Recovery of Function Robotics Double-Blind Method Body Weight Exercise Therapy Spinal Cord Injuries Gait Disorders, Neurologic Humans Female Adult Male
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Use of Hearing Aids Embedded with Inertial Sensors and Artificial Intelligence to Identify Patients at Risk for Falling.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology Dec 17, 2024
OBJECTIVE: To compare fall risk scores of hearing aids embedded with inertial measurement units (IMU-HAs) and powered by artificial intelligence (AI) algorithms with scores by trained observers.
Hearing Loss Postural Balance Double-Blind Method Accelerometry Hearing Aids Humans Artificial Intelligence Prospective Studies Female Aged Aged, 80 and over Male Middle Aged Risk Assessment Accidental Falls
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Non-invasive multiple cancer screening using trained detection canines and artificial intelligence: a prospective double-blind study.

Scientific reports Nov 15, 2024
The specificity and sensitivity of a simple non-invasive multi-cancer screening method in detecting breast, lung, prostate, and colorectal cancer in breath samples were evaluated in a double-blind study. Breath samples of 1386 participants (59.7% mal...
Dogs Neoplasms Lung Neoplasms Early Detection of Cancer Double-Blind Method Prostatic Neoplasms Breast Neoplasms Animals Male Middle Aged Female Aged Humans Adult Artificial Intelligence Sensitivity and Specificity Prospective Studies Colorectal Neoplasms
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Assessing the need for coronary angiography in high-risk non-ST-elevation acute coronary syndrome patients using artificial intelligence and computed tomography.

The international journal of cardiovascular imaging Nov 8, 2024
PURPOSE: This study aimed to evaluate the efficacy of the Chat Generative Pre-trained Transformer (ChatGPT) in guiding the need for invasive coronary angiography (ICA) in high-risk non-ST-elevation (NSTE) acute coronary syndrome (ACS) patients based ...
Humans Artificial Intelligence Decision Support Techniques Prospective Studies Clinical Decision-Making Female Reproducibility of Results Risk Factors Aged Double-Blind Method Coronary Angiography Male Radiographic Image Interpretation, Computer-Assisted Middle Aged Acute Coronary Syndrome Risk Assessment Computed Tomography Angiography Non-ST Elevated Myocardial Infarction Predictive Value of Tests
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