AIMC Topic: Double-Blind Method
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Effects of device-assisted practice of activities of daily living in a close-to-normal pattern on upper extremity motor recovery in individuals with moderate to severe stroke: study protocol of a randomized control trial.
Trials
Jul 4, 2025
BACKGROUND: The majority of individuals with chronic stroke have residual upper extremity (UE) disability which they cite as their greatest barrier to recovery. Using orthoses, robotic devices, and functional electrical stimulation (FES) represent re...
Stroke Rehabilitation
Clinical Protocols
Time Factors
Paresis
Treatment Outcome
Motor Activity
Recovery of Function
Upper Extremity
Robotics
Electric Stimulation Therapy
Disability Evaluation
Double-Blind Method
Equipment Design
Stroke
Activities of Daily Living
Humans
Orthotic Devices
Research Design
Severity of Illness Index
Promethazine for nausea and vomiting prevention after gynaecological laparoscopic surgery: A randomized controlled trial.
Scientific reports
May 8, 2025
Postoperative nausea and vomiting (PONV) represent significant concerns for patients undergoing surgical procedures, as these symptoms greatly impact their postoperative experience. Among female patients undergoing laparoscopic surgery, the incidence...
Step up to triple therapy versus switch to dual bronchodilator therapy in patients with COPD on an inhaled corticosteroid/long-acting β-agonist: post-hoc analyses of KRONOS.
Respiratory research
May 8, 2025
BACKGROUND: In people with chronic obstructive pulmonary disease (COPD) on inhaled corticosteroid/long-acting β-agonist (ICS/LABA) therapy, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommends stepping up to ICS/long-acting mu...
Double-Blind Method
Humans
Drug Therapy, Combination
Female
Male
Drug Substitution
Administration, Inhalation
Aged
Middle Aged
Muscarinic Antagonists
Pulmonary Disease, Chronic Obstructive
Treatment Outcome
Bronchodilator Agents
Adrenal Cortex Hormones
Drug Combinations
Adrenergic beta-2 Receptor Agonists
Towards conversational diagnostic artificial intelligence.
Nature
Apr 9, 2025
At the heart of medicine lies physician-patient dialogue, where skillful history-taking enables effective diagnosis, management and enduring trust. Artificial intelligence (AI) systems capable of diagnostic dialogue could increase accessibility and q...
Random forest and Shapley Additive exPlanations predict oxytocin targeted effects on brain functional networks involved in salience and sensorimotor processing, in a randomized clinical trial in autism.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Apr 2, 2025
Intranasal oxytocin (IN-OXT) has shown some promises in rescuing social deficits in autism spectrum disorder (ASD) as well as some inconsistencies in long-term trials. We conducted a target engagement study to study the precise effects of different d...
Structural and metabolic topological alterations associated with butylphthalide treatment in mild cognitive impairment: Data from a randomized, double-blind, placebo-controlled trial.
Psychiatry and clinical neurosciences
Mar 31, 2025
AIMS: Effective intervention for mild cognitive impairment (MCI) is key for preventing dementia. As a neuroprotective agent, butylphthalide has the potential to treat MCI due to Alzheimer disease (AD). However, the pharmacological mechanism of butylp...
Neurorehabilitation in spinal cord injury: Increased cortical activity through tDCS and robotic gait training.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
Mar 24, 2025
OBJECTIVE: This study investigates the neurophysiological outcomes of combining robot-assisted gait training (RAGT) with active transcranial direct current stimulation (tDCS) on individuals with spinal cord injury (SCI).
Artificial intelligence for individualized treatment of persistent atrial fibrillation: a randomized controlled trial.
Nature medicine
Feb 14, 2025
Although pulmonary vein isolation (PVI) has become the cornerstone ablation procedure for atrial fibrillation (AF), the optimal ablation procedure for persistent and long-standing persistent AF remains elusive. Targeting spatio-temporal electrogram d...
Transcutaneous spinal cord stimulation combined with robotic-assisted body weight-supported treadmill training enhances motor score and gait recovery in incomplete spinal cord injury: a double-blind randomized controlled clinical trial.
Journal of neuroengineering and rehabilitation
Jan 30, 2025
BACKGROUND: Although transcutaneous spinal cord stimulation (tSCS) has been suggested as a safe and feasible intervention for gait rehabilitation, no studies have determined its effectiveness compared to sham stimulation.
Use of Hearing Aids Embedded with Inertial Sensors and Artificial Intelligence to Identify Patients at Risk for Falling.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Dec 17, 2024
OBJECTIVE: To compare fall risk scores of hearing aids embedded with inertial measurement units (IMU-HAs) and powered by artificial intelligence (AI) algorithms with scores by trained observers.
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