AIMC Topic: Early Detection of Cancer

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China Protocol for early screening, precise diagnosis, and individualized treatment of lung cancer.

Signal transduction and targeted therapy
Early screening, diagnosis, and treatment of lung cancer are pivotal in clinical practice since the tumor stage remains the most dominant factor that affects patient survival. Previous initiatives have tried to develop new tools for decision-making o...

Enhancing colorectal polyp segmentation with TCFMA-Net: A transformer-based cross feature and multi-attention network.

Artificial intelligence in medicine
To enhance polyp segmentation in colonoscopy images for early detection and diagnosis of colorectal cancer. The study proposed the Transformer-based cross feature multi-attention network (TCFMA-Net) for polyp segmentation by addressing challenges suc...

Synthesizing [F]PSMA-1007 PET bone images from CT images with GAN for early detection of prostate cancer bone metastases: a pilot validation study.

BMC cancer
BACKGROUND: [F]FDG PET/CT scan combined with [F]PSMA-1007 PET/CT scan is commonly conducted for detecting bone metastases in prostate cancer (PCa). However, it is expensive and may expose patients to more radiation hazards. This study explores deep l...

Identification of a panel of volatile organic compounds in urine for early detection of for bladder cancer.

Scientific reports
The absence of specific markers makes early detection of bladder cancer (BC) challenging. Recent studies have reported the reliable diagnostic significance of volatile organic compounds (VOCs) in several cancers. This study aimed to investigate wheth...

Exploring potential methylation markers for ovarian cancer from cervical scraping samples.

Human genomics
BACKGROUND: Ovarian cancer has the highest mortality rate among gynecological cancers, making early detection crucial, as the five-year survival rate drops from 92% with early-stage diagnosis compared to 31% with late-stage diagnosis. Current diagnos...

Pancreas segmentation using AI developed on the largest CT dataset with multi-institutional validation and implications for early cancer detection.

Scientific reports
Accurate and fully automated pancreas segmentation is critical for advancing imaging biomarkers in early pancreatic cancer detection and for biomarker discovery in endocrine and exocrine pancreatic diseases. We developed and evaluated a deep learning...

Updated Techniques for Melanoma Diagnosis.

Dermatologic clinics
Melanoma, an aggressive skin cancer, requires timely diagnostics for improved patient outcomes. The ABCDE criteria-assessing asymmetry, borders, color, diameter, and evolution-serve as foundational guidelines for early detection. Non-invasive tools l...

Construction of exosome non-coding RNA feature for non-invasive, early detection of gastric cancer patients by machine learning: a multi-cohort study.

Gut
BACKGROUND AND OBJECTIVE: Gastric cancer (GC) remains a prevalent and preventable disease, yet accurate early diagnostic methods are lacking. Exosome non-coding RNAs (ncRNAs), a type of liquid biopsy, have emerged as promising diagnostic biomarkers f...

Optimizing Strategy for Lung Cancer Screening: From Risk Prediction to Clinical Decision Support.

JCO clinical cancer informatics
PURPOSE: Low-dose computed tomography (LDCT) screening is effective in reducing lung cancer mortality by detecting the disease at earlier, more treatable stages. However, high false-positive rates and the associated risks of subsequent invasive diagn...

Explainable Machine Learning Models for Colorectal Cancer Prediction Using Clinical Laboratory Data.

Cancer control : journal of the Moffitt Cancer Center
IntroductionEarly diagnosis of colorectal cancer (CRC) poses a significant clinical challenge. This study aims to develop machine learning (ML) models for CRC risk prediction using clinical laboratory data.MethodsThis retrospective, single-center stu...