AIMC Topic: Elasticity

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Engineering approaches for characterizing soft tissue mechanical properties: A review.

Clinical biomechanics (Bristol, Avon)
From cancer diagnosis to detailed characterization of arterial wall biomechanics, the elastic property of tissues is widely studied as an early sign of disease onset. The fibrous structural features of tissues are a direct measure of its health and f...

Using machine learning to characterize heart failure across the scales.

Biomechanics and modeling in mechanobiology
Heart failure is a progressive chronic condition in which the heart undergoes detrimental changes in structure and function across multiple scales in time and space. Multiscale models of cardiac growth can provide a patient-specific window into the p...

Deep Neural Architectures for Highly Imbalanced Data in Bioinformatics.

IEEE transactions on neural networks and learning systems
In the postgenome era, many problems in bioinformatics have arisen due to the generation of large amounts of imbalanced data. In particular, the computational classification of precursor microRNA (pre-miRNA) involves a high imbalance in the classes. ...

Elasticity Versus Hyperelasticity Considerations in Quasistatic Modeling of a Soft Finger-Like Robotic Appendage for Real-Time Position and Force Estimation.

Soft robotics
Various methods based on hyperelastic assumptions have been developed to address the mathematical complexities of modeling motion and deformation of continuum manipulators. In this study, we propose a quasistatic approach for 3D modeling and real-tim...

Assessment of the stability of citrate-buffered flucloxacillin for injection when stored in two commercially available ambulatory elastomeric devices: INfusor LV (Baxter) and Accufuser (Woo Young Medical): a study compliant with the NHS Yellow Cover Document (YCD) requirements.

European journal of hospital pharmacy : science and practice
OBJECTIVES: To investigate the effect of pH and buffers on the degradation rate of flucloxacillin and to determine if flucloxacillin can be stabilised using a buffered diluent for up to 14 days when stored at 2°C-8°C including a 24-hour infusion peri...

Machine learning-aided exploration of relationship between strength and elastic properties in ascending thoracic aneurysm.

International journal for numerical methods in biomedical engineering
Machine learning was applied to classify tension-strain curves harvested from inflation tests on ascending thoracic aneurysm samples. The curves were classified into rupture and nonrupture groups using prerupture response features. Two groups of feat...

Spine morphology and energetics: how principles from nature apply to robotics.

Bioinspiration & biomimetics
Inspired by the locomotive advantages that an articulated spine enables in quadrupedal animals, we explore and quantify the energetic effect that an articulated spine has in legged robots. We compare two model instances of a conceptual planar quadrup...

Small-scale soft-bodied robot with multimodal locomotion.

Nature
Untethered small-scale (from several millimetres down to a few micrometres in all dimensions) robots that can non-invasively access confined, enclosed spaces may enable applications in microfactories such as the construction of tissue scaffolds by ro...

A deep learning approach to estimate chemically-treated collagenous tissue nonlinear anisotropic stress-strain responses from microscopy images.

Acta biomaterialia
UNLABELLED: Biological collagenous tissues comprised of networks of collagen fibers are suitable for a broad spectrum of medical applications owing to their attractive mechanical properties. In this study, we developed a noninvasive approach to estim...

Elastic network model of learned maintained contacts to predict protein motion.

PloS one
We present a novel elastic network model, lmcENM, to determine protein motion even for localized functional motions that involve substantial changes in the protein's contact topology. Existing elastic network models assume that the contact topology r...