AIMC Topic: Female

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Pharmacokinetics of Eltrombopag in Healthy Chinese Subjects and Effect of Sex and Genetic Polymorphism on its Pharmacokinetic and Pharmacodynamic Variability.

European journal of drug metabolism and pharmacokinetics
BACKGROUND AND OBJECTIVE: Eltrombopag is the first oral, small-molecule, non-peptide thrombopoietin receptor agonist for the treatment of idiopathic thrombocytopenic purpura. This study investigated the pharmacokinetics of eltrombopag in healthy Chin...

Early Coaching to Increase Water Intake in CKD.

Annals of nutrition & metabolism
INTRODUCTION: In observational studies, increased water intake improves kidney function but not in adults with CKD stage 3 and more. CKD WIT trial has shown a nonsignificant gradual decline in kidney function after 1 year of coaching to increase wate...

Effects of a 14-Day Hydration Intervention on Individuals with Habitually Low Fluid Intake.

Annals of nutrition & metabolism
BACKGROUND: Debate continues over whether or not individuals with low total water intake (TWI) are in a chronic fluid deficit (i.e., low total body water) [1]. When women with habitually low TWI (1.6 ± 0.5 L/da...

The Influence of Fluid Intake Behavior on Cognition and Mood among College Students in Baoding, China.

Annals of nutrition & metabolism
INTRODUCTION: Water is a critical nutrient, and it is important for the maintenance of the physiological function of the human body [1-3]. In addition to fluid amounts, f...

U-net model for brain extraction: Trained on humans for transfer to non-human primates.

NeuroImage
Brain extraction (a.k.a. skull stripping) is a fundamental step in the neuroimaging pipeline as it can affect the accuracy of downstream preprocess such as image registration, tissue classification, etc. Most brain extraction tools have been designed...

IL-8, MSPa, MIF, FGF-9, ANG-2 and AgRP collection were identified for the diagnosis of colorectal cancer based on the support vector machine model.

Cell cycle (Georgetown, Tex.)
Colorectal cancer (CRC) is one of the most common cancer, and the early detection of CRC is essential to improve the survival rate of patients. To identify diagnostic markers for colorectal cancer (CRC) by screening differentially expressed proteins ...

Predicting Length of Stay of Coronary Artery Bypass Grafting Patients Using Machine Learning.

The Journal of surgical research
BACKGROUND: There is a growing need to identify which bits of information are most valuable for healthcare providers. The aim of this study was to search for the highest impact variables in predicting postsurgery length of stay (LOS) for patients who...

Detecting the Early Infarct Core on Non-Contrast CT Images with a Deep Learning Residual Network.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
PURPOSE: To explore a new approach mainly based on deep learning residual network (ResNet) to detect infarct cores on non-contrast CT images and improve the accuracy of acute ischemic stroke diagnosis.

A comparison of surgical outcomes among robotic cases performed with an employed surgical assist versus a second surgeon as the assist.

Journal of robotic surgery
To examine whether utilizing an employed surgical first assistant or a physician as an assistant during gynecologic robotic cases affects surgical variables. A high volume gynecologic oncologist's robotic case data spanning fourteen years (2005-2018)...

Predicting postoperative opioid use with machine learning and insurance claims in opioid-naïve patients.

American journal of surgery
BACKGROUND: The clinical impact of postoperative opioid use requires accurate prediction strategies to identify at-risk patients. We utilize preoperative claims data to predict postoperative opioid refill and new persistent use in opioid-naïve patien...