AIMC Topic: Glycoproteins
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Why Protein Modifications Matter for Digestibility: The Case of Ara h 1 Peanut Allergen and Trypsin Cleavage.
Journal of agricultural and food chemistry
Aug 20, 2025
Trypsin is the principal intestinal endopeptidase and proteomics digestion tool, yet the impact of protein modifications (PMs) on digestibility and allergenicity remains underexplored. We employed a proteomic approach to assess trypsin cleavage effic...
Machine learning assisted in Silico discovery and optimization of small molecule inhibitors targeting the Nipah virus glycoprotein.
Scientific reports
May 8, 2025
The Nipah virus (NiV), a lethal pathogen from the Paramyxoviridae family, presents a significant global health threat as a result of its high mortality rate and inter-human transmission. This investigation employed in silico methods that were assiste...
SPRINT-Gly: predicting N- and O-linked glycosylation sites of human and mouse proteins by using sequence and predicted structural properties.
Bioinformatics (Oxford, England)
Oct 15, 2019
MOTIVATION: Protein glycosylation is one of the most abundant post-translational modifications that plays an important role in immune responses, intercellular signaling, inflammation and host-pathogen interactions. However, due to the poor ionization...
High serum YKL-40 level is associated with poor prognosis in patients with lung cancer.
Tuberkuloz ve toraks
Dec 1, 2018
INTRODUCTION: YKL-40 is a glycoprotein that plays role in inflammation and malignant processes. High serum YKL-40 levels are associated with short survive in cancer and chronic obstructive pulmonary disease (COPD) is another reason to increase its' l...
[Changes of platelet rheological behavior and the interventional effects of ulinastatin in rats with high-voltage electrical burns].
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns
Dec 20, 2017
To explore the influence of high-voltage electrical burns on the number of platelet aggregation, β-thromboglobulin (β-TG) and platelet factor 4 (PF-4) and the interventional effects of ulinastatin in rats with high-voltage electrical burns. A total...
[Ulinastatin attenuates hyper-permeability of vascular endothelialium cells induced by serum from patients with sepsis].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology
Dec 1, 2017
Objective To study the effect of ulinastatin (UTI) on the hyper-permeability of human umbilical vein endothelial cell induced by the serum from patients with severe sepsis. Methods The serum level of tumor necrosis factor α (TNF-α) was examined by EL...
[Enhancement of Coprinus cinereus peroxidase in Pichia pastoris by co-expression chaperone PDI and Ero1].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Dec 1, 2015
The 1,095 bp gene encoding peroxidase from Coprinus cinereus was synthesized and integrated into the genome of Pichia pastoris with a highly inducible alcohol oxidase. The recombinant CiP (rCiP) fused with the a-mating factor per-pro leader sequence ...
GESTATIONAL DIABETES MELLITUS SEEMS TO BE ASSOCIATED WITH INFLAMMATION.
Acta clinica Croatica
Dec 1, 2015
The aim of this study was to investigate whether gestational diabetes mellitus (GDM) is associated with inflammation by comparing serum levels of human chitinase-3-like pro- tein 1 (YKL-40), neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte r...
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