AIMC Topic: Gold

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Sensitive and versatile electrogenerated chemiluminescence biosensing platform for protein kinase based on Ru(bpy)3(2+) functionalized gold nanoparticles mediated signal transduction.

Analytica chimica acta
A novel, sensitive and versatile electrogenerated chemiluminescence biosensing platform is developed for monitoring activity and inhibition of protein kinase based on Ru(bpy)3(2+) functionalized gold nanoparticles (Ru(bpy)3(2+)-AuNPs) mediated signal...

Cytotoxic response of platinum-coated gold nanorods in human breast cancer cells at very low exposure levels.

Environmental toxicology
Because of unique optical behavior gold nanorods (GNRs) have attracted attention for the application in biomedical field such as bio-sensing, bio-imaging and hyperthermia. However, toxicological response of GNRs is controversial due to their differen...

Detection and direct readout of drugs in human urine using dynamic surface-enhanced Raman spectroscopy and support vector machines.

Analytical chemistry
A new, novel, rapid method to detect and direct readout of drugs in human urine has been developed using dynamic surface-enhanced Raman spectroscopy (D-SERS) with portable Raman spectrometer on gold nanorods (GNRs) and a classification algorithm call...

The vertices number determined SERS activity of polyhedra and the application in oral cancer detection based on deep learning.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Due to the inherent specificity and high sensitivity, biomedical detections based on Surface-Enhanced Raman Scattering (SERS) technology have garnered increasing attention. In the SERS detection process, fabricating a highly sensitive SERS substrate ...

Microfluidics-based label-free SERS profiling of exosomes with machine learning for osteosarcoma diagnosis.

Talanta
Osteosarcoma (OS) calls for early diagnosis to significantly improve patient survival rates. Exosomes hold significant potential as noninvasive biomarkers for the early diagnosis of cancer. Here, we design a microfluidic device to purify and analyze ...

Fluorescent sensor array for rapid bacterial identification using antimicrobial peptide-functionalized gold nanoclusters and machine learning.

Talanta
Bacterial infectious diseases pose significant challenges to public health, emphasizing the need for rapid and accurate diagnostic tools. Here, we introduced a multichannel fluorescent sensor array based on antimicrobial peptide-functionalized gold n...

Dual-mode nanosensor for sensitive detection of methotrexate based on fluorescence technology and deep learning algorithms.

Analytica chimica acta
BACKGROUND: Methotrexate (MTX) in the body can result in severe, potentially life-threatening side effects. As a result, it is imperative to establish a dependable, precise, and specific method for detecting MTX. However, conventional sensors often s...

Anticoagulation colloidal microrobots based on heparin-mimicking polymers.

Journal of colloid and interface science
Coagulation within blood vessels is a major cause of cardiovascular disease and global mortality, highlighting the urgent need for effective anticoagulant strategies. In this study, we introduce a dynamic and highly efficient anticoagulant platform, ...

Deep Learning-Assisted Nanocavity Sensor for Amphiphilic Biomarker Analysis.

Analytical chemistry
Fluorescence enhancement using nanocavity structures is a promising approach for rapid detection of amphiphilic biomarkers, which are essential for diagnosing diseases such as cancer and infections. This paper presents the use of a silver nanocube (A...

Machine Learning-Driven Multi-Emission Fluorescence Array for Simultaneous Size Discrimination and Quantification of Gold Nanoparticles.

Analytical chemistry
Gold nanoparticles (AuNPs) exhibit size-dependent environmental behaviors and bioaccumulation risks, necessitating precise characterization of their hydrodynamic dimensions and concentrations for toxicity assessment. Existing analytical platforms are...