AIMC Topic: Humans

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Integrating single-cell sequencing and machine learning to uncover the role of mitophagy in subtyping and prognosis of esophageal cancer.

Apoptosis : an international journal on programmed cell death
Globally, esophageal cancer stands as a prominent contributor to cancer-related fatalities, distinguished by its poor prognosis. Mitophagy has a significant impact on the process of cancer progression. This study investigated the prognostic significa...

Evaluation and failure analysis of four commercial deep learning-based autosegmentation software for abdominal organs at risk.

Journal of applied clinical medical physics
PURPOSE: Deep learning-based segmentation of organs-at-risk (OAR) is emerging to become mainstream in clinical practice because of the superior performance over atlas and model-based autocontouring methods. While several commercial deep learning-base...

[Digital innovations in vaccination communication].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Despite the significant success of vaccinations, increasing vaccine hesitancy poses a threat to public health, making effective vaccination communication essential. Both personalized, needs-based conversations between healthcare providers and patient...

Improving reliability of movement assessment in Parkinson's disease using computer vision-based automated severity estimation.

Journal of Parkinson's disease
BackgroundClinical assessments of motor symptoms rely on observations and subjective judgments against standardized scales, leading to variability due to confounders. Improving inter-rater agreement is essential for effective disease management.Objec...

Functional MRI-based machine learning strategy for prediction of postoperative delirium in cardiac surgery patients: A secondary analysis of a prospective observational study.

Journal of clinical anesthesia
STUDY OBJECTIVE: Delirium is a common complication after cardiac surgery and is associated with poor prognosis. An effective delirium prediction model could identify high-risk patients who might benefit from targeted prevention strategies. We introdu...

A Multimodal Deep Learning Approach to Intraoperative Nociception Monitoring: Integrating Electroencephalogram, Photoplethysmography, and Electrocardiogram.

Sensors (Basel, Switzerland)
Monitoring nociception under general anesthesia remains challenging due to the complexity of pain pathways and the limitations of single-parameter methods. In this study, we introduce a multimodal approach that integrates electroencephalogram (EEG), ...

A Novel Improvement of Feature Selection for Dynamic Hand Gesture Identification Based on Double Machine Learning.

Sensors (Basel, Switzerland)
Causal machine learning is an approach that combines causal inference and machine learning to understand and utilize causal relationships in data. In current research and applications, traditional machine learning and deep learning models always focu...

Prediction of cognitive conversion within the Alzheimer's disease continuum using deep learning.

Alzheimer's research & therapy
BACKGROUND: Early diagnosis and accurate prognosis of cognitive decline in Alzheimer's disease (AD) is important to timely assignment to optimal treatment modes. We aimed to develop a deep learning model to predict cognitive conversion to guide re-as...

A multicentre implementation trial of an Artificial Intelligence-driven biomarker to inform Shared decisions for androgen deprivation therapy in men undergoing prostate radiotherapy: the ASTuTE protocol.

BMC cancer
BACKGROUND: Androgen deprivation therapy (ADT) improves outcomes in men undergoing definitive radiotherapy for prostate cancer but carries significant toxicities. Clinical parameters alone are insufficient to accurately identify patients who will der...

A risk prediction model for venous thromboembolism in hospitalized patients with thoracic trauma: a machine learning, national multicenter retrospective study.

World journal of emergency surgery : WJES
BACKGROUND: Early treatment and prevention are the keys to reducing the mortality of VTE in patients with thoracic trauma. This study aimed to develop and validate an automatic prediction model based on machine learning for VTE risk screening in pati...