AIMC Topic: Humans

Clear Filters Showing 1581 to 1590 of 95995 articles

Advancing olfactory perception research with EEG analysis: a dynamic approach of understanding brain responses to almond deterioration.

Food chemistry
Electroencephalography (EEG) enables the investigation of olfactory perception through neuronal electrical activity. Decoding dynamic oscillatory changes in sensory-cognitive processing is critical to understanding odor-induced brain responses. First...

Targeted inhibition of gastric adenocarcinoma by nano-curcumin liposomes: Insights from combined machine learning and experimental analyses into the mechanisms of cuproptosis and metabolic reprogramming.

International journal of pharmaceutics
PURPOSE: Gastric adenocarcinoma is a highly aggressive malignancy characterized by a complex tumor microenvironment. Nano-curcumin liposomes hold great potential in inhibiting tumor growth and survival, as well as inducing cuproptosis and oxidative s...

OmniCLIC: A Unified Omics Contrastive Learning Framework for Effective Integration and Classification of Multiomics Data.

Journal of chemical information and modeling
Integrating multiomics data for cancer subtype classification remains a critical yet challenging task due to the high dimensionality, heterogeneity, and limited interpretability of omics features. To address these limitations, we propose OmniCLIC, a ...

Deep Learning-Based Continuous QT Monitoring to Identify High-Risk Prolongation Events After Class III Antiarrhythmic Initiation.

Circulation
BACKGROUND: Drug-induced QT prolongation after successful inpatient loading of class III antiarrhythmics may occur during routine outpatient care. Insertable cardiac monitors offer continuous signals but are limited by single-lead configuration. We h...

Toward intelligent immune microneedles: Strategies for sensing, therapy, and immune regulation.

Journal of controlled release : official journal of the Controlled Release Society
The human immune system defends against pathogens, regulates inflammation, and supports tissue repair, but overactivity or dysregulation can compromise these functions. While wearable devices have been explored for immune modulation, conventional des...

DCN, NPM3 and SULF1 are hub genes related to vasculogenic mimicry in lung adenocarcinoma.

Journal of cancer research and clinical oncology
AIM: Vasculogenic mimicry (VM), a process in which cancer cells form endothelial cell-independent vascular networks, is a hallmark of tumor aggressiveness in lung adenocarcinoma (LUAD) and supports tumor growth and metastasis. This study aims to iden...

Leveraging Customer Data Platforms for Public Health: a Strategic Perspective.

Journal of medical systems
Public health increasingly relies on digital infrastructures, yet data remains fragmented across clinical, behavioral, and social domains. Customer Data Platforms (CDPs), originally created in marketing to unify diverse information into dynamic indiv...

Synergistic approach utilizing bioinformatics, machine learning, and traditional screening for the identification of novel CSK inhibitors targeting hepatocellular carcinoma.

Journal of computer-aided molecular design
The overexpression or activation of C-terminal Src kinase (CSK) has been recognized as a pivotal factor in the progression of hepatocellular carcinoma (HCC), positioning CSK as a promising therapeutic target. Despite this potential, no CSK-specific i...

Innovations and challenges in vaccine development: Lessons from the SARS-CoV-2 pandemic and prospects.

Biochemical and biophysical research communications
Vaccination stands as one of the most significant achievements in public health, dramatically reducing the incidence of infectious diseases worldwide. The COVID-19 pandemic has catalyzed revolutionary advancements in vaccinology, particularly through...

Advancing Medical Diagnostics: Rapid, Label-Free Detection and Differentiation of Shiga Toxin Variants in Human Serum Using a Cost-Effective PCA-Assisted SERS Platform.

ACS applied materials & interfaces
Shiga toxins-producing (STEC) are zoonotic pathogens causing severe diseases such as hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). Infections caused by STEC represent a public health concern due to the severity of the possible outcom...