AIMC Topic: Humans

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Lung Ultrasound Imaging Dataset for Accurate Detection and Localization of LUS Vertical Artifact.

Scientific data
Lung ultrasound (LUS) vertical artifacts are critical sonographic markers commonly used in evaluating pulmonary conditions such as pulmonary edema, interstitial lung disease, pneumonia, and COVID-19. Accurate detection and localization of these artif...

Single-cell multi-omics uncovers CPS1 as a breast cancer immune evasion therapeutic target.

Scientific reports
Despite significant advances in early detection and therapeutic interventions, breast cancer persists as the most frequently diagnosed malignancy and the leading cause of cancer-related deaths among women globally. Although multiple prognostic signat...

Image-based DNA sequencing encoding for detecting low-mosaicism somatic mobile element insertions.

Nature communications
Active mobile elements in the human genome can create novel mobile element insertions (MEIs) in somatic tissues. Detection of somatic MEIs, particularly those with low mosaicism, remains a significant challenge due to sequencing artifacts and alignme...

Backtracking metabolic dynamics in single cells predicts bacterial replication in human macrophages.

Nature communications
Accurately tracking dynamic state transitions is crucial for modeling and predicting biological outcomes, as it captures heterogeneity of cellular responses. To build a model to predict bacterial infection in single cells, we have monitored in parall...

Clinical Information Extraction From Notes of Veterans With Lymphoid Malignancies: Natural Language Processing Study.

JMIR medical informatics
BACKGROUND: Clinical natural language processing (cNLP) techniques are commonly developed and used to extract information from clinical notes to facilitate clinical decision-making and research. However, they are less established for rare diseases su...

A Machine Learning-Based Scoring System to Identify High Immunoactivity Microsatellite Stability Tumors by Quantifying Similarity to Microsatellite Instability-High Tumors in Colorectal Cancers: Development and Quantitative Study.

JMIR formative research
BACKGROUND: Microsatellite stability (MSS) colorectal cancers (CRCs) have a limited response to immune checkpoint inhibitors (ICIs) compared to microsatellite instability-high (MSI-H) CRCs. Nevertheless, previous studies have shown that some MSS CRCs...

Cancer Metastasis: Therapeutic Challenges and Opportunities.

Medical oncology (Northwood, London, England)
Metastatic cancer is the leading cause of cancer-related mortality, responsible for nearly 90% of deaths worldwide. Its progression depends on a multistep cascade involving invasion, vascular dissemination, survival in circulation and colonization of...

Application of artificial intelligence in esophageal surgery: a systematic review.

Journal of robotic surgery
The aim of this systematic review was to summarize and analyze the available literature on the application of artificial intelligence systems in esophageal surgery, focusing on anatomy recognition, instrument detection, and surgical phase recognition...

Mapping global research landscape and trends in magnetic resonance imaging applications for primary trigeminal neuralgia: a bibliometric analysis.

Neurosurgical review
While magnetic resonance imaging (MRI) has become indispensable in the clinical management of primary trigeminal neuralgia (PTN), a systematic analysis delineating the intellectual structure and evolving trends in this domain remains lacking. This st...

Retinal microvascular differences between multiple sclerosis and neuromyelitis optica spectrum disorder: a cross-sectional study with diagnostic modeling.

Journal of neurology
BACKGROUND AND OBJECTIVES: Retinal alterations in multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) remain unclear, especially the specific patterns and extent of microvascular change. This study aimed to compare these altera...