AIMC Topic: Humans

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A dynamic examination of the digital circuit implementing the Fitzhugh-Nagumo neuron model with emphasis on low power consumption and high precision.

PloS one
Neuromorphic computing has got more attention in various tasks during recent years. The main goal of this field is to explore neural functionality in the brain. The studies of spiking neurons and Spiking Neural Networks (SNNs) are vital to understand...

Factors influencing the adoption of generative artificial intelligence into classroom teaching by university teachers: An empirical study using SPSS PROCESS macros.

PloS one
With the development of science and technology, higher education faces the challenge of AIGC. As one of the central bodies of higher education, it is essential to understand whether teachers accept this new technology and what factors influence their...

Predicting in-hospital mortality in ICU patients with lymphoma using machine learning models.

PloS one
BACKGROUND: Lymphoma is a severe condition with high mortality rates, often requiring ICU admission. Traditional risk stratification tools like SOFA and APACHE scores struggle to capture complex clinical interactions. Machine learning (ML) models off...

Deep learning-based spatial analysis on tumor and immune cells of pathology images predicts MIBC prognosis.

PloS one
OBJECTIVE: Muscle-invasive bladder cancer (MIBC) is a highly aggressive disease with a poor prognosis. This study aims to explore the correlation between the spatial distribution of lymphocyte aggregates and the prognosis of MIBC using deep learning.

SERS technology in virus Detection: Advances, challenges, and future perspectives.

Biosensors & bioelectronics
SERS has revolutionized viral detection with its high sensitivity and specificity. This review comprehensively explores the application progress, challenges, and future directions of SERS in viral detection. Firstly, the fundamental principles of SER...

Anoikis-related genes predicts prognosis and therapeutic response in renal cell carcinoma.

Annals of medicine
BACKGROUND: Metastasis represents the primary cause of cancer-related mortality, with a high incidence observed in renal cell carcinoma (RCC). Anoikis, a specialized form of apoptosis, plays a crucial role in preventing displaced cells from adhering ...

A review on protein corona formation on nanoparticles and prediction of its composition using artificial intelligence tools.

International journal of pharmaceutics
Nanoparticles (NPs) represent critical roles both for drug delivery systems and diagnostics. Nevertheless, due to interaction in a biological medium and specific consequences-like formation of protein corona (PC), changes may happen that have influen...

MMFi-DPBML: Multi-molecular fingerprint feature fusion for predicting ingredient-target interactions in traditional Chinese medicine.

Journal of ethnopharmacology
RESEARCH PURPOSE: This study proposes MMFi-DPBML, a deep learning framework that in-tegrates multi-molecular fingerprint features for predicting ingredient-target interactions (ITIs) in traditional Chinese medicine (TCM). By capturing di-verse struct...

Uncertainty-Aware Deep Learning and Structural Feature Analysis for Reliable Nephrotoxicity Prediction.

Journal of chemical information and modeling
Nephrotoxicity remains a critical safety concern in drug development and clinical practice. Despite their significance, existing computational models for nephrotoxicity prediction face challenges related to limited precision and reliability. To addre...

Unraveling Microstructural and Macrostructural Brain Age Dynamics in Multiple Sclerosis.

Neurology(R) neuroimmunology & neuroinflammation
BACKGROUND AND OBJECTIVES: In multiple sclerosis (MS), neurodegeneration results from the interplay between disease-specific pathology and normal aging. Conventional MRI captures morphologic changes in neurodegeneration, while quantitative MRI (qMRI)...