AIMC Topic: Humans

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Benchmarking reinforcement learning algorithms for autonomous mechanical thrombectomy.

International journal of computer assisted radiology and surgery
PURPOSE: Mechanical thrombectomy (MT) is the gold standard for treating acute ischemic stroke. However, challenges such as operator radiation exposure, reliance on operator experience, and limited treatment access remain. Although autonomous robotics...

ConsisTNet: a spatio-temporal approach for consistent anatomical localization in endoscopic pituitary surgery.

International journal of computer assisted radiology and surgery
PURPOSE: Automated localization of critical anatomical structures in endoscopic pituitary surgery is crucial for enhancing patient safety and surgical outcomes. While deep learning models have shown promise in this task, their predictions often suffe...

B lymphocyte subset-based stratification in primary Sjögren's syndrome: implications for lymphoma risk and personalized treatment.

Clinical rheumatology
OBJECTIVE: This study aimed to perform a detailed stratification analysis of B lymphocyte subsets in patients with primary Sjögren's syndrome (pSS) and to investigate their associations with lymphoma risk, clinical phenotypes, and disease activity.

Gut microbiota-derived extracellular vesicles form a distinct entity from gut microbiota.

mSystems
Extracellular vesicles (EVs), nanoparticles secreted by both gram-negative and gram-positive bacteria, carry various biomolecules and cross biological barriers. Gut microbiota-derived EVs are currently being investigated as a communication mechanism ...

Microbiome and fragmentation pattern of blood cell-free DNA and fecal metagenome enhance colorectal cancer micro-dysbiosis and diagnosis analysis: a proof-of-concept study.

mSystems
Colorectal cancer (CRC) is the third most common cancer, and it can be prevented by performing early screening. As a hallmark of cancer, the human microbiome plays important roles in the occurrence and development of CRC. Recently, the blood microbio...

Development and validation of a novel chronic pancreatitis pathological grade based on artificial intelligence.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
BACKGROUND: Effective chronic pancreatitis (CP) treatment requires accurate severity evaluation, but no histopathology grading system exists. This study aimed to develop and validate a novel CP pathological grade (Histopathology-derived CPpG) using q...

Identification of M2 macrophage-related genes associated with diffuse large B-cell lymphoma via bioinformatics and machine learning approaches.

Biology direct
M2 macrophages play a crucial role in the initiation and progression of various tumors, including diffuse large B-cell lymphoma (DLBCL). However, the characterization of M2 macrophage-related genes in DLBCL remains incomplete. In this study, we downl...

Intelligent predictive risk assessment and management of sarcopenia in chronic disease patients using machine learning and a web-based tool.

European journal of medical research
BACKGROUND: Individuals with chronic diseases are at higher risk of sarcopenia, and precise prediction is essential for its prevention. This study aims to develop a risk scoring model using longitudinal data to predict the probability of sarcopenia i...

Deep learning radiopathomics predicts targeted therapy sensitivity in EGFR-mutant lung adenocarcinoma.

Journal of translational medicine
BACKGROUND: Ttyrosine kinase inhibitors (TKIs) represent the standard first-line treatment for patients with epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma. However, not all patients with EGFR mutations respond to TKIs. This study...