Journal of pharmaceutical and biomedical analysis
Jul 15, 2025
Arsenic (As)-induced hypertension is a significant public health concern, highlighting the need for early risk prediction. This study aimed to develop a predictive model for occupational As exposure and hypertension using metabolomics and machine lea...
BACKGROUND: The exposome framework seeks to unravel the cumulated effects of environmental exposures on health. However, existing methods struggle with challenges including multicollinearity, non-linearity and confounding. To address these limitation...
European journal of clinical pharmacology
Jun 1, 2025
PURPOSE: This study evaluated the performance of three generative AI models-ChatGPT- 4o, Gemini 1.5 Advanced Pro, and Claude 3.5 Sonnet-in producing case-based rational pharmacology questions compared to expert educators.
OBJECTIVE: Electronic health records (EHR) are widely available to complement administrative data-based disease surveillance and healthcare performance evaluation. Defining conditions from EHR is labour-intensive and requires extensive manual labelli...
The aim of this study was to compare the performance of 4 machine learning models-Lasso regression model, random forest model, Boruta algorithm model, and the Boruta algorithm combined with Lasso regression-in predicting stroke risk among hypertensiv...
Studies in health technology and informatics
May 15, 2025
This study investigates the application of a Long Short-Term Memory (LSTM) architecture for classifying hypertension using accelerometer data, specifically focusing on physical activity and sleep from the publicly available NHANES 2011-2012 dataset. ...
OBJECTIVE: Hypertension is a major cardiovascular risk factor affecting about 1 in 3 adults. Although the majority of hypertension cases (∼90%) are classified as "primary hypertension" (PHT), endocrine hypertension (EHT) accounts for ∼10% of cases an...
IMPORTANCE: Hypertension underpins significant global morbidity and mortality. Early lifestyle intervention and treatment are effective in reducing adverse outcomes. Artificial intelligence-enhanced electrocardiography (AI-ECG) has been shown to iden...
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Feb 1, 2025
OBJECTIVE: To enhance the understanding of identifying personalized pharmacotherapy options in Traditional Chinese Medicine (TCM), and further support the registration of new TCM drugs.
Environmental health and preventive medicine
Jan 1, 2025
BACKGROUND: Hypertension is a serious chronic disease that can significantly lead to various cardiovascular diseases, affecting vital organs such as the heart, brain, and kidneys. Our goal is to predict the risk of new onset hypertension using machin...
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