AIMC Topic: Interleukin-10

Clear Filters Showing 1 to 10 of 17 articles

Machine learning-assisted design of immunomodulatory lipid nanoparticles for delivery of mRNA to repolarize hyperactivated microglia.

Drug delivery Mar 3, 2025
Regulating inflammatory microglia presents a promising strategy for treating neurodegenerative and autoimmune disorders, yet effective therapeutic agents delivery to these cells remains a challenge. This study investigates modified lipid nanoparticle...
Mice RNA, Messenger Nanoparticles Lipopolysaccharides Machine Learning Interleukin-10 Drug Delivery Systems Animals Hyaluronic Acid Cell Line Liposomes Lipids Transfection Microglia Green Fluorescent Proteins Immunologic Factors
View on PubMed DOI

StackIL10: A stacking ensemble model for the improved prediction of IL-10 inducing peptides.

PloS one Nov 14, 2024
Interleukin-10, a highly effective cytokine recognized for its anti-inflammatory properties, plays a critical role in the immune system. In addition to its well-documented capacity to mitigate inflammation, IL-10 can unexpectedly demonstrate pro-infl...
Humans Machine Learning Algorithms Interleukin-10 Peptides
View on PubMed DOI

Prediction of six macrophage phenotypes and their IL-10 content based on single-cell morphology using artificial intelligence.

Frontiers in immunology Jan 4, 2024
INTRODUCTION: The last decade has led to rapid developments and increased usage of computational tools at the single-cell level. However, our knowledge remains limited in how extracellular cues alter quantitative macrophage morphology and how such mo...
Cells, Cultured Interleukin-10 Humans Macrophage Colony-Stimulating Factor Macrophages Artificial Intelligence Tumor Necrosis Factor-alpha Cytokines Granulocyte-Macrophage Colony-Stimulating Factor Phenotype Interleukin-4
View on PubMed DOI

Decreased gremlin 1 expression in women with BMI ≥35 kg/m is mediated by interleukin 10 and interleukin 1β in the follicular fluid.

F&S science Jun 29, 2020
OBJECTIVE: To determine how body mass index (BMI) affects the follicular fluid cytokine milieu and investigate how this inflammatory environment impacts cumulus signaling.
Obesity Humans Interleukin-1beta Interleukin-10 Female Follicular Fluid Body Mass Index Intercellular Signaling Peptides and Proteins
View on PubMed DOI

The effects of a therapeutic formalin bath on selected immunological and oxidative stress parameters in common carp (Cyprinus carpio).

The Science of the total environment Nov 5, 2018
Formalin is commonly used as a component of antiparasitic baths in fisheries. In this study the impact of this bath on the immune profile and oxidative stress parameters was evaluated. A formalin bath was prepared in the concentration of 185.3 mg L (...
Interleukin-10 Animals Time Factors Oxidative Stress Carps Interleukin-1beta Gills Formaldehyde Transforming Growth Factor beta Antiparasitic Agents
View on PubMed DOI

Catechin rich butanol fraction extracted from Acacia catechu L. (a thirst quencher) exhibits immunostimulatory potential.

Journal of food and drug analysis Jul 2, 2018
Acacia catechu L., (Fabaceae) named as "catechu" is a plant, the decoction of heartwood of which is daily consumed as thirst quencher by a good percentage of the population in South India. The plant is mainly distributed in India and other Asian coun...
Erythrocytes Acacia Phagocytosis Immunologic Factors Sheep Animals Catechin Mice Plant Extracts Nitric Oxide Interleukin-10 Macrophages
View on PubMed DOI

Gradient Boosted Decision Tree Classification of Endophthalmitis Versus Uveitis and Lymphoma from Aqueous and Vitreous IL-6 and IL-10 Levels.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics Feb 3, 2017
PURPOSE: To investigate the effectiveness of gradient boosting to classify endophthalmitis versus uveitis and lymphoma by intraocular cytokine levels.
Endophthalmitis Interleukin-10 Interleukin-6 Water ROC Curve Lymphoma Decision Trees Data Interpretation, Statistical Uveitis Humans Machine Learning
View on PubMed DOI

Serum profile of cytokines interferon gamma and interleukin-10 in ewes subjected to artificial insemination by cervical retraction.

Theriogenology Dec 23, 2015
This study evaluated the influence of artificial insemination (AI) by cervical retraction (CRI) on serum levels of interferon gamma (IFNγ) and interleukin-10 (IL-10) in ewes. Synchronized pluriparous Santa Inês ewes were subjected to natural mating (...
Interleukin-10 Pregnancy Female Animals Insemination, Artificial Progesterone Interferon-gamma Sheep
View on PubMed DOI

Association of Haemostatic and Inflammatory Biomarkers with Nephropathy in Type 1 Diabetes Mellitus.

Journal of diabetes research Dec 6, 2015
This study aimed at investigating the association between haemostatic biomarkers, proinflammatory, and anti-inflammatory cytokines with chronic kidney disease in type 1 diabetic patients. Patients were divided into two groups: with nephropathy (album...
Fibrin Fibrinogen Degradation Products ADAMTS13 Protein Young Adult Albuminuria Adult Tumor Necrosis Factor-alpha ADAM Proteins Adolescent Male Interleukin-6 von Willebrand Factor Humans Diabetic Nephropathies Biomarkers Middle Aged Interferon-gamma Interleukin-10 Female Diabetes Mellitus, Type 1 Renal Insufficiency, Chronic
View on PubMed DOI

Clinical and inflammatory features based machine learning model for fatal risk prediction of hospitalized COVID-19 patients: results from a retrospective cohort study.

Annals of medicine Dec 1, 2021
OBJECTIVES: To appraise effective predictors for COVID-19 mortality in a retrospective cohort study.
Interleukin-10 Prognosis Retrospective Studies Female Humans Machine Learning COVID-19 Aged, 80 and over Adult Male Cardiovascular Diseases Reproducibility of Results SARS-CoV-2 Hospitalization Aged Ferritins L-Lactate Dehydrogenase Clinical Decision Rules Cohort Studies Hypertension Diabetes Mellitus C-Reactive Protein Middle Aged Comorbidity Severity of Illness Index China
View on PubMed DOI
Popular Topics
Recent Journals