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Limit of Detection

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A MOF-on-MOF heterostructure ratiometric/colorimetric dual-mode fluorescence sensor based on support vector machine for detecting tetracyclines in animal-derived foods.

Food chemistry
The misuse of tetracyclines in livestock production poses significant health risks. Thus, establishing convenient detection methods to replace complex laboratory tests for food safety is crucial. In this study, a heterostructure Zn-BTC/IRMOF-3 (denot...

Improvement of bioanalytical parameters through automation: suitability of a hand-like robotic system.

Analytical and bioanalytical chemistry
Commercial automation systems for small- and medium-sized laboratories, including research environments, are often complex to use. For liquid handling systems (LHS), development is required not only for the robot's movements but also for adapting the...

Neural Network Based Aliasing Spectral Decoupling Algorithm for Precise Mid-Infrared Multicomponent Gases Sensing.

ACS sensors
Owing to the overlapping and cross-interference of absorption lines in multicomponent gases, the simultaneous measurement of such gases via laser absorption spectroscopy frequently necessitates the use of supplementary pressure sensors to distinguish...

High Spatiotemporal Precision Mapping of Optical Nanosensor Array Using Machine Learning.

ACS sensors
Optical nanosensors, including single-walled carbon nanotubes (SWCNTs), provide real-time spatiotemporal reporting at the single-molecule level within a nanometer-scale area. However, their superior sensitivity also makes them susceptible to slight e...

Machine learning-assisted melamine-Cu nanozyme and cholinesterase integrated array for multi-category pesticide intelligent recognition.

Biosensors & bioelectronics
Expanding target pesticide species and intelligent pesticide recognition were formidable challenges for existing cholinesterase inhibition methods. To improve this status, multi-active Mel-Cu nanozyme with mimetic Cu-N sites was prepared for the firs...

Machine learning powered detection of biological toxins in association with confined lateral flow immunoassay (c-LFA).

The Analyst
Biological weapons, primarily dispersed as aerosols, can spread not only to the targeted area but also to adjacent regions following the movement of air driven by wind. Thus, there is a growing demand for toxin analysis because biological weapons are...

Rapid detection of drugs in blood using "molecular hook" surface-enhanced Raman spectroscopy and artificial intelligence technology for clinical applications.

Biosensors & bioelectronics
Accurate detection of cardiovascular drugs in blood is complicated by interference from serum biomolecules. This study introduces a novel surface-enhanced Raman spectroscopy (SERS) platform incorporating "molecular hooks" to capture small drug molecu...

A smartphone-integrated deep learning strategy-assisted rapid detection system for monitoring dual-modal immunochromatographic assay.

Talanta
This study focuses on the integration of a custom-built and optimally trained YOLO v5 model into a smartphone app developed with Java language. A dual-modal immunochromatographic rapid detection system based on a deep learning strategy for smartphone...