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Liver

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Effects of prolonged oxytetracycline supplementation on freshwater stinging catfish (): a multi-biomarker approach.

Frontiers in immunology
BACKGROUND: Aquaculture systems that sporadically depend on antibiotics can contribute to the development of adverse effects on the fish, microbial flora and the environment. This study sought to investigate the impacts of extended oxytetracycline su...

Deep Learning-Enabled Automated Quality Control for Liver MR Elastography: Initial Results.

Journal of magnetic resonance imaging : JMRI
BACKGROUND: Several factors can impair image quality and reliability of liver magnetic resonance elastography (MRE), such as inadequate driver positioning, insufficient wave propagation and patient-related factors.

Impact of deep learning reconstructions on image quality and liver lesion detectability in dual-energy CT: An anthropomorphic phantom study.

Medical physics
BACKGROUND: Deep learning image reconstruction (DLIR) algorithms allow strong noise reduction while preserving noise texture, which may potentially improve hypervascular focal liver lesions.

A machine learning based algorithm accurately stages liver disease by quantification of arteries.

Scientific reports
A major histologic feature of cirrhosis is the loss of liver architecture with collapse of tissue and vascular changes per unit. We developed qVessel to quantify the arterial density (AD) in liver biopsies with chronic disease of varied etiology and ...

Machine learning model to predict the adherence of tuberculosis patients experiencing increased levels of liver enzymes in Indonesia.

PloS one
Indonesia is still the second-highest tuberculosis burden country in the world. The antituberculosis adverse drug reaction and adherence may influence the success of treatment. The objective of this study is to define the model for predicting the adh...

iDIA-QC: AI-empowered data-independent acquisition mass spectrometry-based quality control.

Nature communications
Quality control (QC) in mass spectrometry (MS)-based proteomics is mainly based on data-dependent acquisition (DDA) analysis of standard samples. Here, we collect 2754 files acquired by data independent acquisition (DIA) and paired 2638 DDA files fro...

Analyzing the relationship between gene expression and phenotype in space-flown mice using a causal inference machine learning ensemble.

Scientific reports
Spaceflight has several detrimental effects on human and rodent health. For example, liver dysfunction is a common phenotype observed in space-flown rodents, and this dysfunction is partially reflected in transcriptomic changes. Studies linking trans...

Extracting organs of interest from medical images based on convolutional neural network with auxiliary and refined constraints.

Scientific reports
Accurately extracting organs from medical images provides radiologist with more comprehensive evidences to clinical diagnose, which offers up a higher accuracy and efficiency. However, the key to achieving accurate segmentation lies in abundant clues...

Toward efficient slide-level grading of liver biopsy via explainable deep learning framework.

Medical & biological engineering & computing
In the context of chronic liver diseases, where variability in progression necessitates early and precise diagnosis, this study addresses the limitations of traditional histological analysis and the shortcomings of existing deep learning approaches. ...

Evaluating the synergistic use of advanced liver models and AI for the prediction of drug-induced liver injury.

Expert opinion on drug metabolism & toxicology
INTRODUCTION: Drug-induced liver injury (DILI) is a leading cause of acute liver failure. Hepatotoxicity typically occurs only in a subset of individuals after prolonged exposure and constitutes a major risk factor for the termination of drug develop...