BACKGROUND: Invasive lung adenocarcinoma (LUAD) with the high-grade patterns (HGPs) has the potential for rapid metastasis and frequent recurrence. Therefore, accurately predicting the presence of high-grade components is crucial for doctors to devel...
BACKGROUND: Lung adenocarcinoma (LAC) comprises a substantial subset of non-small cell lung cancer (NSCLC) diagnoses, where epidermal growth factor receptor (EGFR) mutations play a pivotal role as indicators for therapeutic intervention with targeted...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Apr 1, 2025
PURPOSE: The generalization ability of deep learning-based automatic segmentation techniques for lung cancer in practical clinical applications remains under-validated. We reported an investigation that validated a robust semi-supervised conditional ...
Lung cancer exhibits strong heterogeneity, and its early diagnosis and precise subtyping are of great importance, as they can increase the ability to deliver personalized medicines by tailoring therapy regimens. Tissue biopsy, albeit the gold standar...
BACKGROUND: Non-small-cell lung cancer (NSCLC) and its surgery significantly increase the venous thromboembolism (VTE) risk. This study explored the VTE risk factors and established a machine-learning model to predict a failure of postoperative throm...
The growing application of immune checkpoint inhibitors (ICIs) in cancer immunotherapy has underscored the critical need for reliable methods to identify patient populations likely to respond to ICI treatments, particularly in lung cancer treatment. ...
Microorganisms are one of the most promising biomarkers for cancer, and the relationship between microorganisms and lung cancer occurrence and development provides significant potential for pulmonary nodule (PN) diagnosis from a microbiological persp...
Immunotherapy and chemoimmunotherapy are standard treatments for non-oncogene-addicted advanced non-small cell lung cancer (NSCLC). Currently, a limited number of biomarkers, including programmed death-ligand 1 (PD-L1) expression, microsatellite inst...
BACKGROUND: Accurate preoperative prediction of spread through air spaces (STAS) in primary lung adenocarcinoma (LUAD) is critical for optimizing surgical strategies and improving patient outcomes.
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