AIMC Topic: Lung Neoplasms

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Malignancy risk stratification for pulmonary nodules: comparing a deep learning approach to multiparametric statistical models in different disease groups.

European radiology
OBJECTIVES: Incidentally detected pulmonary nodules present a challenge in clinical routine with demand for reliable support systems for risk classification. We aimed to evaluate the performance of the lung-cancer-prediction-convolutional-neural-netw...

Attention-guided CenterNet deep learning approach for lung cancer detection.

Computers in biology and medicine
Lung cancer remains a significant health concern worldwide, prompting ongoing research efforts to enhance early detection and diagnosis. Prior studies have identified key challenges in existing approaches, including limitations in feature extraction,...

Tumor detection on bronchoscopic images by unsupervised learning.

Scientific reports
The diagnosis and early identification of intratracheal tumors relies on the experience of the operators and the specialists. Operations by physicians with insufficient experience may lead to misdiagnosis or misjudgment of tumors. To address this iss...

Identification of key gene signatures for predicting chemo-immunotherapy efficacy in extensive-stage small-cell lung cancer using machine learning.

Lung cancer (Amsterdam, Netherlands)
OBJECTIVES: The lack of definitive biomarkers presents a significant challenge for chemo-immunotherapy in extensive-stage small-cell lung cancer (ES-SCLC). We aimed to identify key genes associated with chemo-immunotherapy efficacy in ES-SCLC through...

Analyzing Secondary Cancer Risk: A Machine Learning Approach.

Asian Pacific journal of cancer prevention : APJCP
OBJECTIVE: Addressing the rising cancer rates through timely diagnosis and treatment is crucial. Additionally, cancer survivors need to understand the potential risk of developing secondary cancer (SC), which can be influenced by several factors incl...

Exploring machine learning tools in a retrospective case-study of patients with metastatic non-small cell lung cancer treated with first-line immunotherapy: A feasibility single-centre experience.

Lung cancer (Amsterdam, Netherlands)
BACKGROUND: Artificial intelligence (AI) models are emerging as promising tools to identify predictive features among data coming from health records. Their application in clinical routine is still challenging, due to technical limits and to explaina...

Towards safe and reliable deep learning for lung nodule malignancy estimation using out-of-distribution detection.

Computers in biology and medicine
Artificial Intelligence (AI) models may fail or suffer from reduced performance when applied to unseen data that differs from the training data distribution, referred to as dataset shift. Automatic detection of out-of-distribution (OOD) data contribu...

Development and validation of a web-based calculator for determining the risk of psychological distress based on machine learning algorithms: A cross-sectional study of 342 lung cancer patients.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
PURPOSE: Early and accurate identification of the risk of psychological distress allows for timely intervention and improved prognosis. Current methods for predicting psychological distress among lung cancer patients using readily available data are ...

Radiomics for differentiating adenocarcinoma and squamous cell carcinoma in non-small cell lung cancer beyond nodule morphology in chest CT.

Scientific reports
Distinguishing between primary adenocarcinoma (AC) and squamous cell carcinoma (SCC) within non-small cell lung cancer (NSCLC) tumours holds significant management implications. We assessed the performance of radiomics-based models in distinguishing ...

Feasibility of AI as first reader in the 4-IN-THE-LUNG-RUN lung cancer screening trial: impact on negative-misclassifications and clinical referral rate.

European journal of cancer (Oxford, England : 1990)
BACKGROUND: Lung cancer screening (LCS) with low-dose CT (LDCT) reduces lung-cancer-related mortality in high-risk individuals. AI can potentially reduce radiologist workload as first-read-filter by ruling-out negative cases. The feasibility of AI as...