AIMC Topic: Lymphocytes

Clear Filters Showing 1 to 10 of 56 articles

Lymphocytes and related inflammatory factors as predictors of metabolic syndrome risk in shift workers: A machine learning approach based on large-scale population data.

PloS one
BACKGROUND: Metabolic syndrome (MetS) is characterized by chronic inflammation and can be worsened by circadian disruption, which is common among shift work. Machine learning can predict the risk of MetS in shift workers using inflammatory biomarkers...

Intracellular lymphocyte protein biomarkers for early radiological triage in the human population.

PloS one
In the event of a large-scale radiological or nuclear emergency, a rapid, high-throughput screening tool will be essential for efficient triage of potentially exposed individuals, optimizing scarce medical resources and ensuring timely care. The obje...

Deep learning-based spatial analysis on tumor and immune cells of pathology images predicts MIBC prognosis.

PloS one
OBJECTIVE: Muscle-invasive bladder cancer (MIBC) is a highly aggressive disease with a poor prognosis. This study aims to explore the correlation between the spatial distribution of lymphocyte aggregates and the prognosis of MIBC using deep learning.

Stroma and lymphocytes identified by deep learning are independent predictors for survival in pancreatic cancer.

Scientific reports
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers known to humans. However, not all patients fare equally poor survival, and a minority of patients even survives advanced disease for months or years. Thus, there is a clinical ...

Combined inflammation-related biomarkers and clinicopathological features for the prognosis of stage II/III colorectal cancer by machine learning.

BMC cancer
BACKGROUND: Inflammation-related biomarkers, such as systemic inflammation score (SIS) and neutrophil-lymphocyte ratio (NLR), are associated with colorectal cancer prognosis. However, the combined role of SIS, NLR, and clinicopathological factors in ...

A novel AI-based score for assessing the prognostic value of intra-epithelial lymphocytes in oral epithelial dysplasia.

British journal of cancer
BACKGROUND: Oral epithelial dysplasia (OED) poses a significant clinical challenge due to its potential for malignant transformation and the lack of reliable prognostic markers. Current OED grading systems do not reliably predict transformation and s...

Prediction of the risk of mortality in older patients with coronavirus disease 2019 using blood markers and machine learning.

Frontiers in immunology
INTRODUCTION: The mortality rate among older people infected with severe acute respiratory syndrome coronavirus 2 is alarmingly high. This study aimed to explore the predictive value of a novel model for assessing the risk of death in this vulnerable...

Computational staining of CD3/CD20 positive lymphocytes in human tissues with experimental confirmation in a genetically engineered mouse model.

Frontiers in immunology
INTRODUCTION: Immune dysregulation plays a major role in cancer progression. The quantification of lymphocytic spatial inflammation may enable spatial system biology, improve understanding of therapeutic resistance, and contribute to prognostic imagi...

Artificial intelligence-based quantification of lymphocytes in feline small intestinal biopsies.

Veterinary pathology
Feline chronic enteropathy is a poorly defined condition of older cats that encompasses chronic enteritis to low-grade intestinal lymphoma. The histological evaluation of lymphocyte numbers and distribution in small intestinal biopsies is crucial for...