The complex interplay between tumor cells and clusters with endothelial tissues during metastasis, in particular with regard to the exosomes in mediating intercellular communication, is still not well understood. Here, we develop a tumoral-transendot...
: Early detection of oncological diseases such as pancreatic ductal adenocarcinoma (PDAC) and ovarian cancer (OV) is pivotal for successful treatment but remains a significant challenge due to the lack of sensitive and specific diagnostic tests. Fluo...
Resistance to chemotherapy of pancreatic ductal adenocarcinoma (PDAC) is largely driven by intratumoral heterogeneity (ITH) due to tumor cell plasticity and clonal diversity. To develop alternative strategies to overcome this defined mechanism of res...
Cancer is a deadly disease that occurs due to the uncontrolled growth of abnormal cells. Bone cancer is the third most occurring disease; approximately 10,000 patients suffer from bone cancer in India annually. It can lead to death if not diagnosed i...
Amorphous solid dispersions (ASD) are an effective strategy for enhancing the solubility and bioavailability of poorly soluble drugs. However, designing and optimizing ASD formulations often rely on extensive dissolution experiments without sufficie...
Dexterous robotic hands have been a central focus in robotics research, aiming to replicate the versatility and functionality of the human hand. This review provides a comprehensive analysis of the latest advancements in the literature on dexterous r...
Aptamers are short, single-stranded DNA or RNA molecules known for their high specificity and affinity toward target biomolecules, making them powerful tools in drug discovery, diagnostics, and biosensing. However, conventional aptamer selection meth...
BACKGROUND AND HYPOTHESIS: Suicide attempt is a complex behavior influenced by a combination of factors including clinical, neurocognitive, and environmental. We aimed to leverage multimodal data collected during pre/early adolescence in research set...
Cow's milk protein allergy (CMA) is one of the most common food allergies in children worldwide. However, it is still not well understood why certain children outgrow their CMA and others do not. While there is increasing evidence for a link of CMA w...
Whereas alignment has been fundamental to sequence-based assessments of protein homology, it is ineffective for intrinsically disordered regions (IDRs) due to their lowered sequence conservation and unique sequence properties. Here, we present a web ...
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