AIMC Topic: Machine Learning

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B lymphocyte subset-based stratification in primary Sjögren's syndrome: implications for lymphoma risk and personalized treatment.

Clinical rheumatology
OBJECTIVE: This study aimed to perform a detailed stratification analysis of B lymphocyte subsets in patients with primary Sjögren's syndrome (pSS) and to investigate their associations with lymphoma risk, clinical phenotypes, and disease activity.

Gut microbiota-derived extracellular vesicles form a distinct entity from gut microbiota.

mSystems
Extracellular vesicles (EVs), nanoparticles secreted by both gram-negative and gram-positive bacteria, carry various biomolecules and cross biological barriers. Gut microbiota-derived EVs are currently being investigated as a communication mechanism ...

Identification of M2 macrophage-related genes associated with diffuse large B-cell lymphoma via bioinformatics and machine learning approaches.

Biology direct
M2 macrophages play a crucial role in the initiation and progression of various tumors, including diffuse large B-cell lymphoma (DLBCL). However, the characterization of M2 macrophage-related genes in DLBCL remains incomplete. In this study, we downl...

Intelligent predictive risk assessment and management of sarcopenia in chronic disease patients using machine learning and a web-based tool.

European journal of medical research
BACKGROUND: Individuals with chronic diseases are at higher risk of sarcopenia, and precise prediction is essential for its prevention. This study aims to develop a risk scoring model using longitudinal data to predict the probability of sarcopenia i...

Development and validation of machine learning models for predicting no. 253 lymph node metastasis in left-sided colorectal cancer using clinical and CT-based radiomic features.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: The appropriate ligation level of the inferior mesenteric artery (IMA) in left-sided colorectal cancer (CRC) surgery is debated, with metastasis in No. 253 lymph node (No. 253 LN) being a key determining factor. This study aimed to develo...

Development and validation of machine learning models for predicting low muscle mass in patients with obesity and diabetes.

Lipids in health and disease
BACKGROUND AND AIMS: Low muscle mass (LMM) is a critical complication in patients with obesity and diabetes, exacerbating metabolic and cardiovascular risks. Novel obesity indices, such as the body roundness index (BRI), conicity index, and relative ...

Development and validation a radiomics combined clinical model predicts treatment response for esophageal squamous cell carcinoma patients.

BMC gastroenterology
PURPOSE: This study is aimed to develop and validate a machine learning model, which combined radiomics and clinical characteristics to predicting the definitive chemoradiotherapy (dCRT) treatment response in esophageal squamous cell carcinoma (ESCC)...

Protein interactions, network pharmacology, and machine learning work together to predict genes linked to mitochondrial dysfunction in hypertrophic cardiomyopathy.

Scientific reports
This study looked at possible targets for hypertrophic cardiomyopathy (HCM), a condition marked by thickening of the ventricular wall, primarily in the left ventricle. We employed differential gene analysis and weighted gene co-expression network ana...

Contrastive learning and mixture of experts enables precise vector embeddings in biological databases.

Scientific reports
The advancement of transformer neural networks has significantly enhanced the performance of sentence similarity models. However, these models often struggle with highly discriminative tasks and generate sub-optimal representations of complex documen...

Predicting Visual Acuity after Retinal Vein Occlusion Anti-VEGF Treatment: Development and Validation of an Interpretable Machine Learning Model.

Journal of medical systems
Accurate prediction of post-treatment visual acuity in macular edema secondary to retinal vein occlusion (RVO-ME) is critical for optimizing anti-VEGF therapy and improving clinical outcomes. While machine learning (ML) has shown promise in ophthalmi...