AIMC Topic: Machine Learning

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The role of senescence-related genes in major depressive disorder: insights from machine learning and single cell analysis.

BMC psychiatry
BACKGROUND: Evidence indicates that patients with Major Depressive Disorder (MDD) exhibit a senescence phenotype or an increased susceptibility to premature senescence. However, the relationship between senescence-related genes (SRGs) and MDD remains...

Explainable machine learning model for predicting acute pancreatitis mortality in the intensive care unit.

BMC gastroenterology
BACKGROUND: Current prediction models are suboptimal for determining mortality risk in patients with acute pancreatitis (AP); this might be improved by using a machine learning (ML) model. In this study, we aimed to construct an explainable ML model ...

Integrating radiomics into predictive models for low nuclear grade DCIS using machine learning.

Scientific reports
Predicting low nuclear grade DCIS before surgery can improve treatment choices and patient care, thereby reducing unnecessary treatment. Due to the high heterogeneity of DCIS and the limitations of biopsies in fully characterizing tumors, current dia...

MRI radiomics based on machine learning in high-grade gliomas as a promising tool for prediction of CD44 expression and overall survival.

Scientific reports
We aimed to predict CD44 expression and assess its prognostic significance in patients with high-grade gliomas (HGG) using non-invasive radiomics models based on machine learning. Enhanced magnetic resonance imaging, along with the corresponding gene...

Machine learning analysis identified NNMT as a potential therapeutic target for hepatocellular carcinoma based on PCD-related genes.

Scientific reports
Programmed cell death (PCD) plays a critical role in cancer biology, influencing tumor progression and treatment response. This study aims to investigate the role of PCD-related genes in hepatocellular carcinoma (HCC), identifying potential prognosti...

High performance fake review detection using pretrained DeBERTa optimized with Monarch Butterfly paradigm.

Scientific reports
In this era of internet, e-commerce has grown tremendously and the customers are increasingly relying on reviews for product information. As these reviews influence the purchasing ability of the future customer, it can give a positive or negative imp...

SeizyML: An Application for Semi-Automated Seizure Detection Using Interpretable Machine Learning Models.

Neuroinformatics
Despite the vast number of publications reporting seizures and the reliance of the field on accurate seizure detection, there is a lack of open-source software tools in the scientific community for automating seizure detection based on electrographic...

Machine learning identifies clinical tumor mutation landscape pathways of resistance to checkpoint inhibitor therapy in NSCLC.

Journal for immunotherapy of cancer
BACKGROUND: Immune checkpoint inhibitors (CPIs) have revolutionized cancer therapy for several tumor indications. However, a substantial fraction of patients treated with CPIs derive no benefit or have short-lived responses to CPI therapy. Identifyin...

Accuracy of machine learning and traditional statistical models in the prediction of postpartum haemorrhage: a systematic review.

BMJ open
OBJECTIVES: To evaluate whether postpartum haemorrhage (PPH) can be predicted using both machine learning (ML) and traditional statistical models.

Graphene-based FETs for advanced biocatalytic profiling: investigating heme peroxidase activity with machine learning insights.

Mikrochimica acta
Graphene-based field-effect transistors (GFETs) are rapidly gaining recognition as powerful tools for biochemical analysis due to their exceptional sensitivity and specificity. In this study, we utilize a GFET system to explore the peroxidase-based b...