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The impact of a simple positioning aid device on the diagnostic performance of thyroid cancer in CT scans: a randomized controlled trial.

Cancer imaging : the official publication of the International Cancer Imaging Society
OBJECTIVE: To evaluate the effectiveness of a simple positioning aid device in neck CT scans for the diagnosis of thyroid cancer, with a focus on its influence on image quality and diagnostic accuracy.

Multiple machine learning algorithms identify 13 types of cell death-critical genes in large and multiple non-alcoholic steatohepatitis cohorts.

Lipids in health and disease
BACKGROUND: Dysregulated programmed cell death pathways mechanistically contribute to hepatic inflammation and fibrogenesis in non-alcoholic steatohepatitis (NASH). Identification of cell death genes may offer insights into diagnostic and therapeutic...

Optimizing the dynamic treatment regime of outpatient rehabilitation in patients with knee osteoarthritis using reinforcement learning.

Journal of neuroengineering and rehabilitation
BACKGROUND: Knee osteoarthritis (KOA) is a prevalent chronic disease worldwide, and traditional treatment methods lack personalized adjustment for individual patient differences and cannot meet the needs of personalized treatment.

Validation of artificial intelligence algorithm LuxIA for screening of diabetic retinopathy from a single 45° retinal colour fundus images: the CARDS study.

BMJ open ophthalmology
OBJECTIVE: This study validated the artificial intelligence (AI)-based algorithm LuxIA for screening more-than-mild diabetic retinopathy (mtmDR) from a single 45° colour fundus image of patients with diabetes mellitus (DM, type 1 or type 2) in Spain....

Identifying most important predictors for suicidal thoughts and behaviours among healthcare workers active during the Spain COVID-19 pandemic: a machine-learning approach.

Epidemiology and psychiatric sciences
AIMS: Studies conducted during the COVID-19 pandemic found high occurrence of suicidal thoughts and behaviours (STBs) among healthcare workers (HCWs). The current study aimed to (1) develop a machine learning-based prediction model for future STBs us...

Early-life and concurrent predictors of the healthy adolescent microbiome in a cohort study.

Genome medicine
BACKGROUND: The microbiome of adolescents is poorly understood, as are factors influencing its composition. We aimed to describe the healthy adolescent microbiome and identify early-life and concurrent predictors of its composition.

Hearing vocals to recognize schizophrenia: speech discriminant analysis with fusion of emotions and features based on deep learning.

BMC psychiatry
BACKGROUND AND OBJECTIVE: Accurate detection of schizophrenia poses a grand challenge as a complex and heterogeneous mental disorder. Current diagnostic criteria rely primarily on clinical symptoms, which may not fully capture individual differences ...

Machine learning-based survival models for predicting rehospitalization of older hip fracture patients: a retrospective cohort study.

BMC musculoskeletal disorders
PURPOSE: To evaluate machine learning-based survival model roles in predicting rehospitalization after hip fractures to improve reduce the burden on the healthcare system.

Altered aminoacid and lipid metabolism in a rat orofacial inflammation model determined by omics approach: potential role in trigeminal sensitisation.

The journal of headache and pain
BACKGROUND: Trigeminal activation and sensitisation involved in chronic inflammatory orofacial pain share several similarities with headaches, including migraine. Therefore, understanding the pathophysiological mechanisms is important to determine no...