White matter hyperintensity (WMH) is a primary manifestation of small vessel disease (SVD), leading to vascular cognitive impairment and other disorders. Accurate WMH quantification is vital for diagnosis and prognosis, but current automatic segmenta...
Clinica chimica acta; international journal of clinical chemistry
Jul 15, 2025
Urothelial carcinoma (UC) is a highly malignant disease with significant public health implications. Despite advancements in oncology, early diagnosis and effective prognostic tools remain limited. This study aimed to develop a machine learning model...
International journal of radiation oncology, biology, physics
Jul 15, 2025
Dramatic strides have been made in real-time adaptive radiation therapy, where treating single tumors as dynamic but rigid bodies has demonstrated a halving of toxicities for prostate cancer. However, the human body is much more complex than a rigid ...
BACKGROUND: Transformer-based neural networks excel in modelling high-dimensional, time-series data with complex dependencies. This proof-of-concept study applies a transformer-X-learner framework to estimate treatment effects using real-world data, ...
BACKGROUND: Major depressive disorder (MDD) presents significant public health challenges due to its increasing prevalence and complex risk factors. This study systematically analyzed data from 2019 to 2023 to explore trends in MDD incidence, symptom...
BACKGROUND: The combination of antidepressant and antipsychotic medication is an effective treatment for major depressive disorder with psychotic features ('psychotic depression'). The present study aims to identify sociodemographic and clinical pred...
BACKGROUND: Clinical studies have shown that facial expressions and body posture in depressed patients differ significantly from those of healthy individuals. Combining relevant behavioral features with artificial intelligence technology can effectiv...
Journal of pharmaceutical and biomedical analysis
Jul 15, 2025
Arsenic (As)-induced hypertension is a significant public health concern, highlighting the need for early risk prediction. This study aimed to develop a predictive model for occupational As exposure and hypertension using metabolomics and machine lea...
Prolonged wakefulness is known to adversely affect basic cognitive abilities such as object recognition and decision-making. It affects the dynamics of neuronal networks in the brain and can even lead to hallucinations and epileptic seizures. In cogn...
STUDY OBJECTIVES: The manual annotation of polysomnography (PSG) hypnograms is difficult and time-consuming. U-Sleep is an alternative, fast, and publicly available, automated sleep staging system evaluated in adult PSGs. In this study, we compare th...
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