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Prediction of suicide using web based voice recordings analyzed by artificial intelligence.

Scientific reports
The integration of machine learning (ML) and deep learning models in suicide risk assessment has advanced significantly in recent years. In this study, we utilized ML in a case-control design, we predicted completed suicides using publicly available,...

Sperm metabolomic signatures of asthenozoospermia and teratozoospermia in Chinese reproductive-age men.

Scientific reports
Asthenozoospermia and teratozoospermia are common causes of male infertility. Despite their prevalence, the underlying metabolic mechanisms remain poorly understood. In this study, we conducted targeted metabolomic profiling of sperm samples from 131...

3BTRON: A Blood-Brain Barrier Recognition Network.

Communications biology
The blood-brain barrier (BBB) plays a crucial role in maintaining brain homeostasis. During ageing, the BBB undergoes structural alterations. Electron microscopy (EM) is the gold standard for studying the structural alterations of the brain vasculatu...

A robust machine learning approach to predicting remission and stratifying risk in rheumatoid arthritis patients treated with bDMARDs.

Scientific reports
Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting millions worldwide, leading to inflammation, joint damage, and reduced quality of life. Although biological disease-modifying antirheumatic drugs (bDMARDs) are effective, they are co...

Predictive analysis of pediatric gastroenteritis risk factors and seasonal variations using VGG Dense HybridNetClassifier a novel deep learning approach.

Scientific reports
Pediatric gastroenteritis is a major reason for sickness and death among children worldwide, especially in places where healthcare and clean sanitation are scarce. Conventional methods of diagnosis overlook possible risks and seasonal trends, which r...

Leveraging pathological markers of lower grade glioma to predict the occurrence of secondary epilepsy, a retrospective study.

Scientific reports
Epilepsy is a common manifestation in patients with lower grade glioma (LGG), often presenting as the initial symptom in approximately 70% of cases. This study aimed to identify clinical and pathological markers for epileptic seizures in patients wit...

5-Hydroxymethylcytosine signatures as diagnostic biomarkers for septic cardiomyopathy.

Scientific reports
At present, there are currently no molecular biomarkers for the early diagnosis of sepsis cardiomyopathy (SCM) in clinical practice. This study focuses on an in-depth examination of the DNA hydroxymethylation profiles within plasma extracellular vesi...

Utility of synthetic musculoskeletal gaits for generalizable healthcare applications.

Nature communications
Deep-neural-network-based artificial intelligence enables quantitative gait analysis with commodity sensors. However, current gait-analysis models are usually specialized for specific clinical populations and sensor settings due to the limited size a...

Co-Design of a Health Screening Program Fact Sheet by People Experiencing Homelessness and ChatGPT: Focus Group Study.

JMIR formative research
BACKGROUND: People experiencing homelessness have worse oral health outcomes and a notable health informational asymmetry compared to the general population. Screening programs present a viable option for this population; however, barriers to access,...

The interplay between homeostatic synaptic scaling and homeostatic structural plasticity maintains the robust firing rate of neural networks.

eLife
Critical network states and neural plasticity enable adaptive behavior in dynamic environments, supporting efficient information processing and experience-dependent learning. Synaptic-weight-based Hebbian plasticity and homeostatic synaptic scaling a...