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Development and validation of CT-based fusion model for preoperative prediction of invasion and lymph node metastasis in adenocarcinoma of esophagogastric junction.

BMC medical imaging
PURPOSE: In the context of precision medicine, radiomics has become a key technology in solving medical problems. For adenocarcinoma of esophagogastric junction (AEG), developing a preoperative CT-based prediction model for AEG invasion and lymph nod...

Construction and validation of HBV-ACLF bacterial infection diagnosis model based on machine learning.

BMC infectious diseases
OBJECTIVE: To develop and validate a novel diagnostic model for detecting bacterial infections in patients with hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) using advanced machine learning algorithms. The focus is on improving ...

Lactylation associated biomarkers and immune infiltration in aortic dissection.

Scientific reports
Protein lactylation, a novel post-translational modification (PTM), has emerged as a critical factor in disease processes related to glycolysis and immune responses. However, its role in aortic dissection (AD) has yet to be thoroughly investigated. T...

Validation of an AI-enabled exome/transcriptome liquid biopsy platform for early detection, MRD, disease monitoring, and therapy selection for solid tumors.

Scientific reports
Effective clinical management of patients with cancer requires highly accurate diagnosis, precise therapy selection, and highly sensitive monitoring of disease burden. Caris Assure is a multifunctional blood-based assay that couples whole exome and w...

Muscle-Driven prognostication in gastric cancer: A multicenter deep learning framework integrating Iliopsoas and erector spinae radiomics for 5-Year survival prediction.

Scientific reports
This study developed a 5-year survival prediction model for gastric cancer patients by combining radiomics and deep learning, focusing on CT-based 2D and 3D features of the iliopsoas and erector spinae muscles. Retrospective data from 705 patients ac...

Profiling short-term longitudinal severity progression and associated genes in COVID-19 patients using EHR and single-cell analysis.

Scientific reports
Here we propose CovSF, a deep learning model designed to track and forecast short-term severity progression of COVID-19 patients using longitudinal clinical records. The motivation stems from the need for timely medical resource allocation, improved ...

Development of a machine learning model to identify the predictors of the neonatal intensive care unit admission.

Scientific reports
Scientists aim to create a system that can predict the likelihood of newborns being admitted to the neonatal intensive care unit (NICU) by combining various statistical methods. This prediction could potentially reduce the negative health outcomes, d...

A machine learning-based framework for predicting metabolic syndrome using serum liver function tests and high-sensitivity C-reactive protein.

Scientific reports
Metabolic Syndrome (MetS) comprises a clustering of conditions that significantly increase the risk of heart disease, stroke, and diabetes. Timely detection and intervention are crucial in preventing severe health outcomes. In this study, we implemen...

Development and evaluation of an automated classification and counting system for rice planthoppers captured on survey boards.

Scientific reports
Rice planthoppers are the most economically important insect pests of rice in Asia. Traditional surveys to examine their abundance and composition in paddy fields involve human visual inspection, which requires considerable time and effort by expert ...

Comparison of physician and large language model chatbot responses to online ear, nose, and throat inquiries.

Scientific reports
Large language models (LLMs) can potentially enhance the accessibility and quality of medical information. This study evaluates the reliability and quality of responses generated by ChatGPT-4, an LLM-driven chatbot, compared to those written by physi...