AIMC Topic: Mice

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Mitochondria Segmentation From EM Images via Hierarchical Structured Contextual Forest.

IEEE journal of biomedical and health informatics
Delineation of mitochondria from electron microscopy (EM) images is crucial to investigate its morphology and distribution, which are directly linked to neural dysfunction. However, it is a challenging task due to the varied appearances, sizes and sh...

Visual Servoed Robotic Mouse Oocyte Rotation.

IEEE transactions on bio-medical engineering
UNLABELLED: Both injection and biopsy of a mammalian cell require positioning and orientation of a biological cell in a three-dimensional space under a microscope. Manual cell manipulation and orientation is the most commonly used method that is base...

Bio-transformation of green tea infusion with tannase and its improvement on adipocyte metabolism.

Enzyme and microbial technology
Catechins in green tea possess various health benefits. Enzymatic treatment improves physiological activities by inducing bioconversion of catechins. Here, we investigated the effect of green tea infusion (GT) after tannase treatment, which transform...

Super-Soft and Super-Elastic DNA Robot with Magnetically Driven Navigational Locomotion for Cell Delivery in Confined Space.

Angewandte Chemie (International ed. in English)
Soft organisms such as earthworms can access confined, narrow spaces, inspiring scientists to fabricate soft robots for in vivo manipulation of cells or tissues and minimally invasive surgery. We report a super-soft and super-elastic magnetic DNA hyd...

Efficient identification of novel anti-glioma lead compounds by machine learning models.

European journal of medicinal chemistry
Glioblastoma multiforme (GBM) is the most devastating and widespread primary central nervous system tumor. Pharmacological treatment of this malignance is limited by the selective permeability of the blood-brain barrier (BBB) and relies on a single d...

A novel Cerenkov luminescence tomography approach using multilayer fully connected neural network.

Physics in medicine and biology
Cerenkov luminescence tomography (CLT) has been proved as an effective tool for various biomedical applications. Because of the severe scattering of Cerenkov luminescence, the performance of CLT remains unsatisfied. This paper proposed a novel CLT re...

Epigallocatechin gallate has antibacterial and antibiofilm activity in methicillin resistant and susceptible of different lineages in non-cytotoxic concentrations.

Natural product research
is an opportunistic agent that can cause a variety of infections, both hospital and community-acquired. Epigallocatechin gallate (EGCG), a flavonoid present in the leaves of , has different biological activities, including antimicrobial potential. H...

AI-powered transmitted light microscopy for functional analysis of live cells.

Scientific reports
Transmitted light microscopy can readily visualize the morphology of living cells. Here, we introduce artificial-intelligence-powered transmitted light microscopy (AIM) for subcellular structure identification and labeling-free functional analysis of...

Deep learning enables pathologist-like scoring of NASH models.

Scientific reports
Non-alcoholic fatty liver disease (NAFLD) and the progressive form of non-alcoholic steatohepatitis (NASH) are diseases of major importance with a high unmet medical need. Efficacy studies on novel compounds to treat NAFLD/NASH using disease models a...

Soft Ring-Shaped Cellu-Robots with Simultaneous Locomotion in Batches.

Advanced materials (Deerfield Beach, Fla.)
Untethered mini-robots can move single cells or aggregates to build complex constructs in confined spaces and may enable various biomedical applications such as regenerative repair in medicine and biosensing in bioengineering. However, a significant ...