AIMC Topic: Middle Aged

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Macrolide combination therapy for patients hospitalised with community-acquired pneumonia? An individualised approach supported by machine learning.

The European respiratory journal Dec 12, 2019
BACKGROUND: The role of macrolide/β-lactam combination therapy in community-acquired pneumonia (CAP) of moderate severity is a matter of debate. Macrolides expand the coverage to atypical pathogens and attenuate pulmonary inflammation, but have been ...
Hospitalization Aged Aged, 80 and over Adult Male Humans Machine Learning Anti-Bacterial Agents Prospective Studies Female Propensity Score Macrolides Pneumonia, Bacterial Community-Acquired Infections beta-Lactams Middle Aged Severity of Illness Index Treatment Outcome Europe Drug Therapy, Combination
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Preoperative prediction of tumour deposits in rectal cancer by an artificial neural network-based US radiomics model.

European radiology Dec 11, 2019
OBJECTIVE: To develop a machine learning-based ultrasound (US) radiomics model for predicting tumour deposits (TDs) preoperatively.
Magnetic Resonance Imaging Rectal Neoplasms Preoperative Period Extranodal Extension Aged Humans Adult Neural Networks, Computer Male Machine Learning Middle Aged Prospective Studies Ultrasonography Female
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Radiomics allows for detection of benign and malignant histopathology in patients with metastatic testicular germ cell tumors prior to post-chemotherapy retroperitoneal lymph node dissection.

European radiology Dec 11, 2019
OBJECTIVES: To evaluate whether a computed tomography (CT) radiomics-based machine learning classifier can predict histopathology of lymph nodes (LNs) after post-chemotherapy LN dissection (pcRPLND) in patients with metastatic non-seminomatous testic...
Retroperitoneal Space Neoplasms, Germ Cell and Embryonal Lymphatic Metastasis Testicular Neoplasms Orchiectomy Lymph Node Excision Adult Male Middle Aged Computational Biology Lymph Nodes Neoplasm Staging Machine Learning Humans Retrospective Studies Tomography, X-Ray Computed Reproducibility of Results Young Adult
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Predicting long-term type 2 diabetes with support vector machine using oral glucose tolerance test.

PloS one Dec 11, 2019
Diabetes is a large healthcare burden worldwide. There is substantial evidence that lifestyle modifications and drug intervention can prevent diabetes, therefore, an early identification of high risk individuals is important to design targeted preven...
Adult Diabetes Mellitus, Type 2 Glucose Tolerance Test Humans Insulin Resistance Male Machine Learning United States Life Style Biomarkers Body Mass Index Middle Aged Female Support Vector Machine Blood Glucose Insulin
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Feasibility study for use of angiographic parametric imaging and deep neural networks for intracranial aneurysm occlusion prediction.

Journal of neurointerventional surgery Dec 10, 2019
BACKGROUND: Angiographic parametric imaging (API), based on digital subtraction angiography (DSA), is a quantitative imaging tool that may be used to extract contrast flow parameters related to hemodynamic conditions in abnormal pathologies such as i...
Male Middle Aged Deep Learning Treatment Outcome Predictive Value of Tests Humans Neural Networks, Computer Female Adult Feasibility Studies Angiography, Digital Subtraction Intracranial Aneurysm
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Comparison of Initial Experience with Transrectal Magnetic Resonance Imaging Cognitive Guided Micro-Ultrasound Biopsies versus Established Transperineal Robotic Ultrasound Magnetic Resonance Imaging Fusion Biopsies for Prostate Cancer.

The Journal of urology Dec 10, 2019
PURPOSE: We compared cancer detection rates in patients who underwent magnetic resonance imaging cognitive guided micro-ultrasound biopsy vs robotic ultrasound magnetic resonance imaging fusion biopsy for prostate cancer.
Reproducibility of Results Cognition Humans Follow-Up Studies Aged Retrospective Studies Prostate Robotics Male Neoplasm Grading Rectum Middle Aged Ultrasonography, Interventional Image-Guided Biopsy Ultrasonography Magnetic Resonance Imaging, Interventional Perineum
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Artificial intelligence for detecting small FDG-positive lung nodules in digital PET/CT: impact of image reconstructions on diagnostic performance.

European radiology Dec 10, 2019
OBJECTIVES: To evaluate the diagnostic performance of a deep learning algorithm for automated detection of small F-FDG-avid pulmonary nodules in PET scans, and to assess whether novel block sequential regularized expectation maximization (BSREM) reco...
Lung Neoplasms Multiple Pulmonary Nodules Solitary Pulmonary Nodule Positron Emission Tomography Computed Tomography Radiopharmaceuticals Sensitivity and Specificity Male Middle Aged Deep Learning Image Processing, Computer-Assisted Fluorodeoxyglucose F18 Humans Artificial Intelligence Algorithms Retrospective Studies Female Aged Aged, 80 and over Adult
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Evaluating the reliability of neurocognitive biomarkers of neurodegenerative diseases across countries: A machine learning approach.

NeuroImage Dec 10, 2019
Accurate early diagnosis of neurodegenerative diseases represents a growing challenge for current clinical practice. Promisingly, current tools can be complemented by computational decision-support methods to objectively analyze multidimensional meas...
Aged Aged, 80 and over Male Middle Aged Magnetic Resonance Imaging Alzheimer Disease Frontotemporal Dementia Neuropsychological Tests Atrophy Executive Function Humans Machine Learning Biomarkers Female Reproducibility of Results
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Comparison of machine learning algorithms for the identification of acute exacerbations in chronic obstructive pulmonary disease.

Computer methods and programs in biomedicine Dec 9, 2019
OBJECTIVES: Identifying acute exacerbations in chronic obstructive pulmonary disease (AECOPDs) is of utmost importance for reducing the associated mortality and financial burden. In this research, the authors aimed to develop identification models fo...
ROC Curve Logistic Models Aged Support Vector Machine Humans Pulmonary Disease, Chronic Obstructive Predictive Value of Tests Machine Learning Sensitivity and Specificity Bayes Theorem Algorithms Male Electronic Health Records Middle Aged Female
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Robot-assisted versus manual navigated stereoelectroencephalography in adult medically-refractory epilepsy patients.

Epilepsy research Dec 9, 2019
OBJECTIVE: Stereoelectroencephalography (SEEG) has experienced a recent growth in adoption for epileptogenic zone (EZ) localization. Advances in robotics have the potential to improve the efficiency and safety of this intracranial seizure monitoring ...
Robotics Electroencephalography Neurosurgical Procedures Stereotaxic Techniques Drug Resistant Epilepsy Adult Male Middle Aged Treatment Outcome Brain Mapping Humans Retrospective Studies Female
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