AIMC Topic: Middle Aged

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A predictive model for MGMT promoter methylation status in glioblastoma based on terahertz spectral data.

Analytical biochemistry
O-methylguanine-DNA methyltransferase (MGMT) promoter methylation is a crucial biomarker in glioblastoma (GBM) that influences response to temozolomide. Traditional detection methods, such as gene sequencing, are time-consuming and limited to postope...

Deep Learning Based on Ultrasound Images Differentiates Parotid Gland Pleomorphic Adenomas and Warthin Tumors.

Ultrasonic imaging
Exploring the clinical significance of employing deep learning methodologies on ultrasound images for the development of an automated model to accurately identify pleomorphic adenomas and Warthin tumors in salivary glands. A retrospective study was c...

Effectiveness of a community intervention program on healthy lifestyles (PREDICOL) among adults with prediabetes in two Latin American cities: A quasi-experimental study.

Primary care diabetes
PURPOSE: This study aimed to measure the impact of a community-based lifestyle modification intervention program on the Health-Related Quality of Life (HRQoL) of adults with prediabetes in two Latin American cities.

Handwriting strokes as biomarkers for Alzheimer's disease prediction: A novel machine learning approach.

Computers in biology and medicine
In recent years, machine learning-based handwriting analysis has emerged as a valuable tool for supporting the early diagnosis of Alzheimer's disease and predicting its progression. Traditional approaches represent handwriting tasks using a single fe...

A cross-sectional study comparing machine learning and logistic regression techniques for predicting osteoporosis in a group at high risk of cardiovascular disease among old adults.

BMC geriatrics
BACKGROUND: Osteoporosis has become a significant public health concern that necessitates the application of appropriate techniques to calculate disease risk. Traditional methods, such as logistic regression,have been widely used to identify risk fac...

Machine learning-based risk prediction model for arteriovenous fistula stenosis.

European journal of medical research
BACKGROUND: Arteriovenous fistula stenosis is a common complication in hemodialysis patients, yet effective predictive tools are lacking. This study aims to develop an interpretable machine learning model for stenosis risk prediction.

Exploring non-invasive biomarkers for pulmonary nodule detection based on salivary microbiomics and machine learning algorithms.

Scientific reports
Microorganisms are one of the most promising biomarkers for cancer, and the relationship between microorganisms and lung cancer occurrence and development provides significant potential for pulmonary nodule (PN) diagnosis from a microbiological persp...

Combination of exhaled volatile organic compounds with serum biomarkers predicts respiratory infection severity.

Pulmonology
OBJECTIVE: During respiratory infections, host-pathogen interaction alters metabolism, leading to changes in the composition of expired volatile organic compounds (VOCs) and soluble immunomodulators. This study aims to identify VOC and blood biomarke...

Deep learning-based prediction of cervical canal stenosis from mid-sagittal T2-weighted MRI.

Skeletal radiology
OBJECTIVE: This study aims to establish a large degenerative cervical myelopathy cohort and develop deep learning models for predicting cervical canal stenosis from sagittal T2-weighted MRI.