Glycogen storage disease (GSD) is a group of rare inherited metabolic disorders characterized by abnormal glycogen storage and breakdown. These disorders are caused by mutations in G6PC1, which is essential for proper glucose storage and metabolism. ...
Understanding speech in noisy environments is a primary challenge for individuals with hearing loss, affecting daily communication and quality of life. Traditional speech-in-noise tests are essential for screening and diagnosing hearing loss but are ...
OBJECTIVES: This study aims to develop a reliable and interpretable predictive model for long-term survival in Type A aortic dissection (TAAD) patients, utilizing machine learning (ML) algorithms.
INTRODUCTION: Aging is characterized by gradual structural and functional changes in the body over time, with intervertebral disc degeneration (IVDD) representing a key manifestation of spinal aging and a major contributor to low back pain (LBP).
Frontiers in cellular and infection microbiology
Apr 15, 2025
OBJECTIVE: Metagenomic next-generation sequencing (mNGS) can potentially detect various pathogenic microorganisms without bias to improve the diagnostic rate of fever of unknown origin (FUO), but there are no effective methods to predict mNGS-positiv...
PURPOSE: Artificial Intelligence (AI) has been shown to enhance fracture-detection-accuracy, but the most effective AI-implementation in clinical practice is less well understood. In the current study, four approaches to AI-implementation are evaluat...
Computer methods and programs in biomedicine
Apr 14, 2025
BACKGROUND: Osteoarthritis (OA) is a common degenerative joint disease, particularly affecting individuals aged >50 years. It deteriorates quality of life and restricts physical activity in the elderly. Early diagnosis of OA is crucial for effective ...
PURPOSE: Fluorescence imaging is critical for intraoperative intestinal perfusion assessment in colorectal surgery, yet its clinical adoption remains limited by subjective interpretation and lack of quantitative standards. This study introduces an in...