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A deep learning method for real-time intraoperative US image segmentation in prostate brachytherapy.

International journal of computer assisted radiology and surgery
PURPOSE: This paper addresses the detection of the clinical target volume (CTV) in transrectal ultrasound (TRUS) image-guided intraoperative for permanent prostate brachytherapy. Developing a robust and automatic method to detect the CTV on intraoper...

Deep in the Bowel: Highly Interpretable Neural Encoder-Decoder Networks Predict Gut Metabolites from Gut Microbiome.

BMC genomics
BACKGROUND: Technological advances in next-generation sequencing (NGS) and chromatographic assays [e.g., liquid chromatography mass spectrometry (LC-MS)] have made it possible to identify thousands of microbe and metabolite species, and to measure th...

Cross-species regulatory sequence activity prediction.

PLoS computational biology
Machine learning algorithms trained to predict the regulatory activity of nucleic acid sequences have revealed principles of gene regulation and guided genetic variation analysis. While the human genome has been extensively annotated and studied, mod...

Challenges of machine learning model validation using correlated behaviour data: Evaluation of cross-validation strategies and accuracy measures.

PloS one
Automated monitoring of the movements and behaviour of animals is a valuable research tool. Recently, machine learning tools were applied to many species to classify units of behaviour. For the monitoring of wild species, collecting enough data for t...

Neuro-fuzzy patch-wise R-CNN for multiple sclerosis segmentation.

Medical & biological engineering & computing
The segmentation of the lesion plays a core role in diagnosis and monitoring of multiple sclerosis (MS). Magnetic resonance imaging (MRI) is the most frequent image modality used to evaluate such lesions. Because of the massive amount of data, manual...

Structure equation model and neural network analyses to predict coronary artery lesions in Kawasaki disease: a single-centre retrospective study.

Scientific reports
A new method to predict coronary artery lesions (CALs) in Kawasaki disease (KD) was developed using a mean structure equation model (SEM) and neural networks (Nnet). There were 314 admitted children with KD who met at least four of the six diagnostic...

Automatic CT image segmentation of maxillary sinus based on VGG network and improved V-Net.

International journal of computer assisted radiology and surgery
PURPOSE: The analysis of the maxillary sinus (MS) can provide an assessment for many clinical diagnoses, so accurate CT image segmentation of the MS is essential. However, common segmentation methods are mainly done by experienced doctors manually, a...

Realistic simulation of virtual multi-scale, multi-modal patient trajectories using Bayesian networks and sparse auto-encoders.

Scientific reports
Translational research of many disease areas requires a longitudinal understanding of disease development and progression across all biologically relevant scales. Several corresponding studies are now available. However, to compile a comprehensive pi...

Evaluation of marker selection methods and statistical models for chronological age prediction based on DNA methylation.

Legal medicine (Tokyo, Japan)
In forensic investigation, retrieving biological information from DNA evidence is a promising field of interest. One of the applications is on the estimation of the age of the donor based on DNA methylation. A large number of studies focused on age p...