AIMC Topic: Muscle, Skeletal

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Multiphoton microscopy and tissue clearing for 3D characterization of the vasculature and fibrosis remodeling in rat dystrophic skeletal muscle.

Scientific reports
Duchenne muscular dystrophy (DMD) is characterized by progressive muscle fiber degeneration and replacement by fibrous and adipose tissues, alongside significant vascular abnormalities. Traditional two-dimensional (2D) histological assessments provid...

Efficient elastic tissue motions indicate general motor skill.

Scientific reports
Insights into the general nature of motor skill could fundamentally change how we develop movement abilities, with implications for musculoskeletal well-being and injury. Here, we sought to identify indicators of general motor skill-those shared by e...

3D deep learning-based muscle volume quantification from thoracic CT as a surrogate for DXA-Derived appendicular muscle mass in older adults.

Aging clinical and experimental research
BACKGROUND: In order to identify patients with sarcopenia, the use of routine imaging could provide valuable support. One of the most common radiological examinations, especially in geriatric inpatient care, is CT thoracic imaging. Therefore, it woul...

Real-time biofeedback monitoring rehabilitation of distal radius fracture.

Journal of neuroengineering and rehabilitation
BACKGROUND: Elderly patients often face challenges in recovering from distal radius fractures (DRFs), and inadequately guided rehabilitation may lead to delayed healing or secondary injury.

Microenvironment-driven satellite cell regeneration and repair in aging-related sarcopenia: mechanisms and therapeutic frontiers.

Stem cell research & therapy
Sarcopenia, a progressive age-related decline in skeletal muscle mass and function, is closely linked to impaired regenerative capacity of satellite cells (SCs), also known as satellite cells. Age-dependent SCs dysfunction, driven by intrinsic senesc...

Motor unit number estimation based on convolutional neural network.

Journal of neural engineering
. The compound muscle action potential (CMAP) scan contains a muscle's detailed stimulus-activation information and thereby can be used for motor unit number estimation (MUNE). Due to the challenges in accurately obtaining the motor unit numbers from...

Association between fat-to-muscle ratio and secondary osteoporosis in rheumatoid arthritis: a cross-sectional study at a tertiary hospital in China.

BMJ open
OBJECTIVES: To investigate the correlation between fat-to-muscle ratio (FMR) or other body composition and secondary osteoporosis (OP) in patients with rheumatoid arthritis (RA) and to develop a predictive model using FMR and related clinical factors...

Construct prediction models for low muscle mass with metabolic syndrome using machine learning.

PloS one
BACKGROUND: Metabolic syndrome (MetS) and sarcopenia are major global public health problems, and their coexistence significantly increases the risk of death. In recent years, this trend has become increasingly prominent in younger populations, posin...

Optogenetic neuromuscular actuation of a miniature electronic biohybrid robot.

Science robotics
Neuronal control of skeletal muscle function is ubiquitous across species for locomotion and doing work. In particular, emergent behaviors of neurons in biohybrid neuromuscular systems can advance bioinspired locomotion research. Although recent stud...

Enhanced gastrocnemius-mimicking lower limb powered exoskeleton robot.

Journal of neuroengineering and rehabilitation
BACKGROUND: Lower limb muscle bionic devices have attracted significant attention in rehabilitation and assistive sports technology. Despite advancements in mimicking human movement, current devices still face challenges in enhancing strength and mov...