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Neoplasm Invasiveness

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Propofol affects the growth and metastasis of pancreatic cancer via ADAM8.

Pharmacological reports : PR
BACKGROUND: Anesthesia is a major component of surgery and recently considered an important regulator of cell phenotypes. Here we aimed to investigate propofol, an anesthesia drug, in suppressing pancreatic cancer (PDAC), focusing on A disintegrin an...

Machine Learning Approaches to Radiogenomics of Breast Cancer using Low-Dose Perfusion Computed Tomography: Predicting Prognostic Biomarkers and Molecular Subtypes.

Scientific reports
Radiogenomics investigates the relationship between imaging phenotypes and genetic expression. Breast cancer is a heterogeneous disease that manifests complex genetic changes and various prognosis and treatment response. We investigate the value of m...

Breast cancer histopathology image classification through assembling multiple compact CNNs.

BMC medical informatics and decision making
BACKGROUND: Breast cancer causes hundreds of thousands of deaths each year worldwide. The early stage diagnosis and treatment can significantly reduce the mortality rate. However, the traditional manual diagnosis needs intense workload, and diagnosti...

Machine learning-based prediction of breast cancer growth rate in vivo.

British journal of cancer
BACKGROUND: Determining the rate of breast cancer (BC) growth in vivo, which can predict prognosis, has remained elusive despite its relevance for treatment, screening recommendations and medicolegal practice. We developed a model that predicts the r...

Classification for invasion depth of esophageal squamous cell carcinoma using a deep neural network compared with experienced endoscopists.

Gastrointestinal endoscopy
BACKGROUND AND AIMS: Cancer invasion depth is a critical factor affecting the choice of treatment in patients with superficial squamous cell carcinoma (SCC). However, the diagnosis of invasion depth is currently subjective and liable to interobserver...