In cancer, the primary tumour's organ of origin and histopathology are the strongest determinants of its clinical behaviour, but in 3% of cases a patient presents with a metastatic tumour and no obvious primary. Here, as part of the ICGC/TCGA Pan-Can...
BACKGROUND: Anesthesia is a major component of surgery and recently considered an important regulator of cell phenotypes. Here we aimed to investigate propofol, an anesthesia drug, in suppressing pancreatic cancer (PDAC), focusing on A disintegrin an...
International journal of computer assisted radiology and surgery
Nov 13, 2019
PURPOSE: As some of the most important factors for treatment decision of lung cancer (which is the deadliest neoplasm) are staging and histology, this work aimed to associate quantitative contrast-enhanced computed tomography (CT) features from malig...
Medical & biological engineering & computing
Aug 15, 2019
Fuzzy inference systems have been frequently used in medical diagnosis for managing uncertainty sources in the medical images. In addition, fuzzy systems have high level of interpretability because of using linguistic terms for knowledge representati...
Computer methods and programs in biomedicine
Jun 22, 2019
BACKGROUND AND OBJECTIVES: Prediction of lymph node metastasis (LNM) for early colorectal cancer (CRC) is critical for determining treatment strategies after endoscopic resection. Some histologic parameters for predicting LNM have been established, b...
International journal of computer assisted radiology and surgery
May 25, 2019
PURPOSE: The gold standard for colorectal cancer metastases detection in the peritoneum is histological evaluation of a removed tissue sample. For feedback during interventions, real-time in vivo imaging with confocal laser microscopy has been propos...
PURPOSE: Recent advances in machine learning have enabled better understanding of large and complex visual data. Here, we aim to investigate patient outcome prediction with a machine learning method using only an image of tumour sample as an input.
Clinical cancer research : an official journal of the American Association for Cancer Research
Apr 22, 2019
PURPOSE: Tumors are continuously evolving biological systems, and medical imaging is uniquely positioned to monitor changes throughout treatment. Although qualitatively tracking lesions over space and time may be trivial, the development of clinicall...
This study aimed to identify the optimal radiomic machine-learning classifier for differentiating glioblastoma (GBM) from solitary brain metastases (MET) preoperatively. Four hundred and twelve patients with solitary brain tumors (242 GBM and 170 sol...
International journal of computer assisted radiology and surgery
Mar 9, 2019
PURPOSE: Dual-energy X-ray absorptiometry (DEXA) studies are used for screening patients for low bone mineral density (BMD). Patients with breast and prostate cancer are often treated with hormone-altering drugs that result in low BMD. These patients...