Investigations on epithelial-mesenchymal transition (EMT) events occurring on circulating tumor cells (CTCs) are poised to significantly advance nanoliquid biopsy methodologies. This study presented a colorimetric multiplex lateral flow immunoassay s...
Heterogeneity in cancer is known to be a contributor to the formation of metastatic lesions, poor prognosis, and ultimately undermines therapeutic efficacy. This same tumor heterogeneity is reflected in circulating tumor cells (CTCs) and tumor derive...
The global burden of cancer is rising, with treatment failures often due to the metastatic nature of late-stage malignancies. Circulating tumour cells (CTCs) are metastatic precursors shed from primary tumours, which survive in circulation, extravasa...
BACKGROUND: Circulating tumor cells (CTCs) in peripheral blood are crucial for prognosis, treatment response, disease monitoring, and personalized therapy. However, identifying CTCs remains challenging due to their scarcity and heterogeneity, even wi...
Colorectal cancer (CRC) is a major global health issue. Despite advancements in treatment, CRC patients still face challenges of metastasis and variable prognosis. Circulating tumor cells (CTCs) shed from the primary tumor into the peripheral blood c...
Circulating tumor cells (CTCs) are promising biomarkers for cancer diagnosis, while detecting CTCs in clinical samples is still challenging due to the scarcity and heterogeneity of CTCs. Herein, a triple-mode sensing platform based on an antifouling ...
International journal of molecular sciences
May 23, 2025
Liquid biopsy has gained attention in oncology as a non-invasive diagnostic tool, offering valuable insights into tumor biology through the analysis of circulating nucleic acid (cfDNA and cfRNA), circulating tumor cells (CTCs), extracellular vesicles...
BACKGROUND: CT images and circulating tumor cells (CTCs) are indispensable for diagnosing the mediastinal lesions by providing radiological and intra-tumoral information. This study aimed to develop and validate a deep multimodal fusion network (DMFN...
Circulating tumor cells (CTCs) are vital indicators of metastasis and provide a non-invasive method for early cancer diagnosis, prognosis, and therapeutic monitoring. However, their low prevalence and heterogeneity in the bloodstream pose significant...
The precise separation and focusing of circulating tumor cells (CTCs) from blood cells are crucial for advancing cancer diagnosis, optimizing therapeutic strategies, and fostering progress in cellular research. Inertial microfluidics offers an effici...
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