AIMC Topic: Nomograms

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CT Differentiation and Prognostic Modeling in COVID-19 and Influenza A Pneumonia.

Academic radiology
RATIONALE AND OBJECTIVES: This study aimed to compare CT features of COVID-19 and Influenza A pneumonia, develop a diagnostic differential model, and explore a prognostic model for lesion resolution.

Predicting 30-day mortality in hemophagocytic lymphohistiocytosis: clinical features, biochemical parameters, and machine learning insights.

Annals of hematology
This study aims to evaluate the clinical characteristics and biochemical parameters of hemophagocytic lymphohistiocytosis (HLH) patients to predict 30-day mortality. Parameters analyzed include lymphocyte count (L), platelet count (PLT), total protei...

Machine learning-driven ultrasound radiomics for assessing axillary lymph node burden in breast cancer.

Frontiers in endocrinology
OBJECTIVE: This study explores the value of combining intratumoral and peritumoral radiomics features from ultrasound imaging with clinical characteristics to assess axillary lymph node burden in breast cancer patients.

Integrating ultrasound radiomics and clinicopathological features for machine learning-based survival prediction in patients with nonmetastatic triple-negative breast cancer.

BMC cancer
OBJECTIVE: This study aimed to evaluate the predictive value of implementing machine learning models based on ultrasound radiomics and clinicopathological features in the survival analysis of triple-negative breast cancer (TNBC) patients.

Identification of benzo(a)pyrene-related toxicological targets and their role in chronic obstructive pulmonary disease pathogenesis: a comprehensive bioinformatics and machine learning approach.

BMC pharmacology & toxicology
BACKGROUND: Chronic obstructive pulmonary disease (COPD) pathogenesis is influenced by environmental factors, including Benzo(a)pyrene (BaP) exposure. This study aims to identify BaP-related toxicological targets and elucidate their roles in COPD dev...

Machine learning-based identification of co-expressed genes in prostate cancer and CRPC and construction of prognostic models.

Scientific reports
The objective of this study was to employ machine learning to identify shared differentially expressed genes (DEGs) in prostate cancer (PCa) initiation and castration resistance, aiming to establish a robust prognostic model and enhance understanding...

Machine learning-based bulk RNA analysis reveals a prognostic signature of 13 cell death patterns and potential therapeutic target of SMAD3 in acute myeloid leukemia.

BMC cancer
BACKGROUND: Dysregulation or abnormality of the programmed cell death (PCD) pathway is closely related to the occurrence and development of many tumors, including acute myeloid leukemia (AML). Studying the abnormal characteristics of PCD pathway-rela...

A diagnostic model for sepsis using an integrated machine learning framework approach and its therapeutic drug discovery.

BMC infectious diseases
BACKGROUND: Sepsis remains a life-threatening condition in intensive care units (ICU) with high morbidity and mortality rates. Some biomarkers commonly used in clinic do not have the characteristics of rapid and specific growth and rapid decline afte...

Developing a nomogram model for predicting non-obstructive azoospermia using machine learning techniques.

Scientific reports
Azoospermia, defined by the absence of sperm in the ejaculate, manifests as obstructive azoospermia (OA) or non-obstructive azoospermia (NOA). Reliable predictive models utilizing biomarkers could aid in clinical decision-making. This study included ...

Prediction of mortality risk in critically ill patients with systemic lupus erythematosus: a machine learning approach using the MIMIC-IV database.

Lupus science & medicine
OBJECTIVE: Early prediction of long-term outcomes in patients with systemic lupus erythematosus (SLE) remains a great challenge in clinical practice. Our study aims to develop and validate predictive models for the mortality risk.