1-photon (1p) calcium imaging is an increasingly prevalent method in behavioral neuroscience. Numerous analysis pipelines have been developed to improve the reliability and scalability of pre-processing and ROI extraction for these large calcium ima...
Deep-learning workflows of microscopic image analysis are sufficient for handling the contextual variations because they employ biological samples and have numerous tasks. The use of well-defined annotated images is important for the workflow. Cancer...
International journal of computer assisted radiology and surgery
May 22, 2020
PURPOSE: The cup-to-disc ratio (CDR), a clinical metric of the relative size of the optic cup to the optic disc, is a key indicator of glaucoma, a chronic eye disease leading to loss of vision. CDR can be measured from fundus images through the segme...
PURPOSE: To develop deep learning models for detecting reticular pseudodrusen (RPD) using fundus autofluorescence (FAF) images or, alternatively, color fundus photographs (CFP) in the context of age-related macular degeneration (AMD).
The diagnostic possibilities of multiphoton tomography (MPT) in dermatology have already been demonstrated. Nevertheless, the analysis of MPT data is still time-consuming and operator dependent. We propose a fully automatic approach based on convolut...
Large-scale fluorescence calcium imaging methods have become widely adopted for studies of long-term hippocampal and cortical neuronal dynamics. Pyramidal neurons of the rodent hippocampus show spatial tuning in freely foraging or head-fixed navigati...
In this research, machine learning including the genetic algorithm (GA) and support vector machine (SVM) algorithm is used to solve the "low up-conversion luminescence (UCL) intensity" problem in order to find the optimal phosphor with enhanced red U...
Quantifying the extent to which points are clustered in single-molecule localization microscopy data is vital to understanding the spatial relationships between molecules in the underlying sample. Many existing computational approaches are limited in...
European journal of clinical nutrition
Mar 16, 2020
Estimates of body composition have been derived using 3-dimensional optical imaging (3DO), but no equations to date have been calibrated using a 4-component (4C) model criterion. This investigation reports the development of a novel body fat predicti...
Optical tissue transparency permits scalable cellular and molecular investigation of complex tissues in 3D. Adult human organs are particularly challenging to render transparent because of the accumulation of dense and sturdy molecules in decades-age...
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