AIMC Topic: Osteoporosis
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Artificial intelligence for predicting the risk of bone fragility fractures in osteoporosis.
European radiology experimental
Jun 24, 2025
Osteoporosis is widespread with a high incidence rate, resulting in fragility fractures which are a major contributor to mortality among the elderly. Artificial intelligence (AI), in particular artificial neural networks, appears to be useful in mana...
Bridging Genomic Research Disparities in Osteoporosis GWAS: Insights for Diverse Populations.
Current osteoporosis reports
May 24, 2025
PURPOSE OF REVIEW: Genome-wide association studies (GWAS) have significantly advanced osteoporosis research by identifying genetic loci associated with bone mineral density (BMD) and fracture risk. However, disparities persist due to the underreprese...
Humans
Machine Learning
Bone Density
Osteoporotic Fractures
African People
Low Density Lipoprotein Receptor-Related Protein-5
Core Binding Factor Alpha 1 Subunit
Asian People
White People
Gene-Environment Interaction
Osteoporosis
Genome-Wide Association Study
Genomics
Genetic Predisposition to Disease
Resting-State Functional MRI Reveals Altered Seed-Based Connectivity in Diabetic Osteoporosis Patients.
Clinical interventions in aging
May 21, 2025
BACKGROUND: Diabetic osteoporosis (DOP) can cause abnormal brain neural activity, but its mechanism is still unclear. This study aims to further explore the abnormal functional connectivity between different brain regions based on the team's previous...
Accelerated ultrashort echo time quantitative magnetization transfer (UTE-qMT) imaging of macromolecular fraction (MMF) in cortical bone based on a self-attention convolutional neural network.
Magnetic resonance imaging
May 4, 2025
PURPOSE: To combine ultrashort echo time quantitative magnetization transfer (UTE-qMT) imaging with a self-attention convolutional neural network (SAT-Net) for accelerated mapping of macromolecular fraction (MMF) in cortical bone.
Deep Learning-enhanced Opportunistic Osteoporosis Screening in Ultralow-Voltage (80 kV) Chest CT: A Preliminary Study.
Academic radiology
May 2, 2025
RATIONALE AND OBJECTIVES: To explore the feasibility of deep learning (DL)-enhanced, fully automated bone mineral density (BMD) measurement using the ultralow-voltage 80 kV chest CT scans performed for lung cancer screening.
Using artificial intelligence-based software for an unbiased discrimination of immune cell subtypes in the fracture hematoma and bone marrow of non-osteoporotic and osteoporotic mice.
PloS one
Apr 29, 2025
It is well established that the early inflammatory response following fracture is essential for initiating subsequent bone regeneration. An imbalance in inflammation, whether within the innate or adaptive immune response, can result in impaired fract...
Automated opportunistic screening for osteoporosis using deep learning-based automatic segmentation and radiomics on proximal femur images from low-dose abdominal CT.
BMC musculoskeletal disorders
Apr 17, 2025
RATIONALE AND OBJECTIVES: To establish an automated osteoporosis detection model based on low-dose abdominal CT (LDCT). This model combined a deep learning-based automatic segmentation of the proximal femur with a radiomics-based bone status classifi...
A prediction model of pediatric bone density from plain spine radiographs using deep learning.
Scientific reports
Apr 15, 2025
Osteoporosis, a bone disease characterized by decreased bone mineral density (BMD) resulting in decreased mechanical strength and an increased fracture risk, remains poorly understood in children. Herein, we developed/validated a deep learning-based ...
The Role of ChatGPT in osteoporosis management: a comparative analysis with clinical expertise.
Archives of osteoporosis
Apr 9, 2025
UNLABELLED: This study evaluates the role of ChatGPT in osteoporosis management, demonstrating 91% diagnostic accuracy and significantly faster response times compared to clinicians. The findings highlight the potential for artificial intelligence (A...
Machine learning models to predict osteoporosis in patients with chronic kidney disease stage 3-5 and end-stage kidney disease.
Scientific reports
Apr 3, 2025
Chronic kidney disease-mineral bone disorder is a common complication in patients with chronic kidney disease (CKD) and end-stage kidney disease (ESKD), and it increases the risk of osteoporosis and fractures. This study aimed to develop predictive m...
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