AIMC Topic: Predictive Value of Tests

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A pilot study for the prediction of liver function related scores using breath biomarkers and machine learning.

Scientific reports
Volatile organic compounds (VOCs) present in exhaled breath can help in analysing biochemical processes in the human body. Liver diseases can be traced using VOCs as biomarkers for physiological and pathophysiological conditions. In this work, we pro...

Diagnostic performance of deep learning and computational fluid dynamics-based instantaneous wave-free ratio derived from computed tomography angiography.

BMC cardiovascular disorders
BACKGROUND AND OBJECTIVES: Both fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are widely used to evaluate ischemia-causing coronary lesions. A new method of CT-iFR, namely AccuiFRct, for calculating iFR based on deep learning ...

Establishment and External Validation of a Hypoxia-Derived Gene Signature for Robustly Predicting Prognosis and Therapeutic Responses in Glioblastoma Multiforme.

BioMed research international
OBJECTIVE: Hypoxia presents a salient feature investigated in most solid tumors that holds key roles in cancer progression, including glioblastoma multiforme (GBM). Here, we aimed to construct a hypoxia-derived gene signature for identifying the high...

Deep learning based diagnosis for cysts and tumors of jaw with massive healthy samples.

Scientific reports
We aimed to develop an explainable and reliable method to diagnose cysts and tumors of the jaw with massive panoramic radiographs of healthy peoples based on deep learning, since collecting and labeling massive lesion samples are time-consuming, and ...

Deep learning-based segmentation of the thorax in mouse micro-CT scans.

Scientific reports
For image-guided small animal irradiations, the whole workflow of imaging, organ contouring, irradiation planning, and delivery is typically performed in a single session requiring continuous administration of anaesthetic agents. Automating contourin...

A neuromorphic spiking neural network detects epileptic high frequency oscillations in the scalp EEG.

Scientific reports
Interictal High Frequency Oscillations (HFO) are measurable in scalp EEG. This development has aroused interest in investigating their potential as biomarkers of epileptogenesis, seizure propensity, disease severity, and treatment response. The deman...

Arterial enhancing local tumor progression detection on CT images using convolutional neural network after hepatocellular carcinoma ablation: a preliminary study.

Scientific reports
To evaluate the performance of a deep convolutional neural network (DCNN) in detecting local tumor progression (LTP) after tumor ablation for hepatocellular carcinoma (HCC) on follow-up arterial phase CT images. The DCNN model utilizes three-dimensio...

Dynamic Bayesian networks for prediction of health status and treatment effect in patients with chronic lymphocytic leukemia.

Scientific reports
Chronic lymphocytic leukemia (CLL) is the most common blood cancer in adults. The course of CLL and patients' response to treatment are varied. This variability makes it difficult to select the most appropriate treatment regimen and predict the progr...

Differentiation of intestinal tuberculosis and Crohn's disease through an explainable machine learning method.

Scientific reports
Differentiation between Crohn's disease and intestinal tuberculosis is difficult but crucial for medical decisions. This study aims to develop an effective framework to distinguish these two diseases through an explainable machine learning (ML) model...

Evaluation of a deep learning model on coronary CT angiography for automatic stenosis detection.

Diagnostic and interventional imaging
PURPOSE: The purpose of this study was to evaluate a deep-learning model (DLM) for classifying coronary arteries on coronary computed tomography -angiography (CCTA) using the Coronary Artery Disease-Reporting and Data System (CAD-RADS).