FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Dec 15, 2025
Intracerebral hemorrhage (ICH) is a major cause of death and disability worldwide. Despite treatment advances, reliable prognostic biomarkers are still lacking. While phagocytosis regulation is implicated in ICH pathogenesis, its potential for diagno...
UNLABELLED: Precision oncology is becoming increasingly integral to clinical practice, demonstrating notable improvements in treatment outcomes. Whereas molecular data provide comprehensive insights, obtaining such data remains costly and time-consum...
This study aimed to comprehensively investigate the regulatory mechanism and clinical value of secreted phosphoprotein 1 (SPP1) in the three-stage progression of "smoking-chronic obstructive pulmonary disease (COPD)-carcinogenesis" in lung squamous ...
BACKGROUND: Accurately predicting hematoma enlargement (HE) is crucial for improving the prognosis of patients with cerebral haemorrhage. Artificial intelligence (AI) is a potentially reliable assistant for medical image recognition. This study syste...
Gliomas exhibit significant heterogeneity and diverse molecular subtypes, and there are marked differences in treatment strategies and prognoses for gliomas of different grades and molecular types. However, current glioma molecular subtyping systems ...
OBJECTIVES: Pancreatic cancer treatment plans involving surgery and/or chemotherapy are highly dependent on disease stage. However, current staging systems are ineffective and poorly correlated with survival outcomes. We investigate how artificial in...
INTRODUCTION: A new perspective on cancer metabolism suggests that it varies by context and is diverse. Cancer metabolism reprogramming can create a heterogeneous microenvironment that affects immune cell infiltration and function, complicating the s...
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
Dec 1, 2025
BACKGROUND: Idiopathic intracranial hypertension (IIH) is a vision-threatening disorder mainly affecting women of a reproductive age. Prompt diagnosis and intervention are vital to prevent vision loss, but validated tools to predict visual outcomes a...
The spine journal : official journal of the North American Spine Society
Dec 1, 2025
BACKGROUND CONTEXT: Survival prediction models for patients with spinal metastases are crucial for guiding clinical decision-making and optimizing treatment strategies. Renal cell carcinoma spinal metastases (RCC-SM) present unique challenges due to ...
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Dec 1, 2025
BACKGROUND: Early prediction of pregnancy complications is important for adequate and timely prevention, management, and reducing maternal/fetal pathogenesis.
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