AIMC Topic: Prognosis

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PDualNet: a deep learning framework for joint prediction of Parkinson's disease progression subtype and MDS-UPDRS scores.

Scientific reports
Parkinson's disease is one of the most common and complex neurodegenerative diseases, characterized by remarkable motor and cognitive decline. As it is a highly heterogeneous disorder, i.e., the specific symptoms, their severity, and their progressio...

Identification of novel biomarkers for epithelial ovarian cancer through machine learning and explainable artificial intelligence using in silico and in vitro analysis.

Scientific reports
Epithelial ovarian cancer (EOC) is a lethal gynecological malignancy. Ongoing research aimed to identify novel biomarkers and develop combined algorithms to improve diagnosis and prognosis prediction for EOC. RNA-seq related to EOC were obtained from...

Development and validation of a machine learning model to predict early recurrence after surgery in NSCLC patients.

Scientific reports
To develop and validate a machine learning (ML) model for predicting early recurrence (ER) within two years post-surgery in non-small cell lung cancer (NSCLC) patients. This multicenter cohort study included 3,171 NSCLC patients who underwent radical...

Novel insights into predicting the presence of micropapillary and solid components in stage IA lung adenocarcinoma using machine learning models of modifiable risk factors.

Annals of medicine
BACKGROUND: Lung adenocarcinoma (LUAC) patients with micropapillary (MP) and/or solid (S) generally demonstrate a poorer survival prognosis. In the diagnosis and treatment of stage IA LUAC, precisely establishing personalized treatment strategies for...

A SWI/SNF complex-related genes signature predicts prognosis and immune infiltration in ccRCC with KCNK5 as a novel biomarker.

Scientific reports
Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma (RCC). Although we have made many achievements in the therapy of RCC with the progress of medicine, the clinical management of metastatic RCC remains a dauntin...

Hybrid deep learning framework for cardiovascular disease diagnosis and prognosis using GAN, LSTM, GRU, VARMA, and deep DynaQ network.

Scientific reports
Cardiovascular diseases (CVDs) are a major cause of morbidity and mortality worldwide. Effective CVD treatment requires early and accurate diagnosis. CVD diagnosis and prognosis can be done using medical image analysis. In this paper, we propose a no...

Multimodal deep learning framework integrating multiphase CT and histopathological whole slide imaging for predicting recurrence in ccRCC.

Scientific reports
ccRCC is an aggressive, heterogeneous tumor with a poor prognosis. Prognostic assessments need multi-modal data. Radiological images have limits, while pathological images offer micro-level details. Integrating these for ccRCC outcome prediction is i...

Development and validation of the risk stratification based on deep learning and radiomics to predict survival of advanced cervical cancer.

Scientific reports
Advanced cervical cancer (aCC) is associated with a poor prognosis. This study aimed to develop and validate a deep learning-based risk stratification model to predict overall survival in aCC patients using pre-treatment CT images. A total of 396 pat...

Worse survival despite indolent features for triple-negative invasive lobular carcinoma: a Swedish nationwide registry-based study.

Breast cancer research and treatment
PURPOSE: To evaluate differences in clinical outcomes, treatments received, recurrence, and sociodemographic characteristics in patients with triple-negative breast cancer (TNBC) classified as invasive lobular carcinoma (TNBC-ILC) or invasive carcino...