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Radiotherapy Dosage

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MRI-based treatment planning for brain stereotactic radiosurgery: Dosimetric validation of a learning-based pseudo-CT generation method.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists
Magnetic resonance imaging (MRI)-only radiotherapy treatment planning is attractive since MRI provides superior soft tissue contrast without ionizing radiation compared with computed tomography (CT). However, it requires the generation of pseudo CT f...

Knowledge-Based Planning for Identifying High-Risk Stereotactic Ablative Radiation Therapy Treatment Plans for Lung Tumors Larger Than 5 cm.

International journal of radiation oncology, biology, physics
PURPOSE: Stereotactic ablative body radiation therapy (SABR) for lung tumors ≥5 cm can be associated with more toxicity than that for smaller tumors. We investigated the relationship between dosimetry and toxicity and used a knowledge-based planning ...

Automated prediction of dosimetric eligibility of patients with prostate cancer undergoing intensity-modulated radiation therapy using a convolutional neural network.

Radiological physics and technology
The quality of radiotherapy has greatly improved due to the high precision achieved by intensity-modulated radiation therapy (IMRT). Studies have been conducted to increase the quality of planning and reduce the costs associated with planning through...

Artificial intelligence in radiation oncology: A specialty-wide disruptive transformation?

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Artificial intelligence (AI) is emerging as a technology with the power to transform established industries, and with applications from automated manufacturing to advertising and facial recognition to fully autonomous transportation. Advances in each...

MR-Only Brain Radiation Therapy: Dosimetric Evaluation of Synthetic CTs Generated by a Dilated Convolutional Neural Network.

International journal of radiation oncology, biology, physics
PURPOSE: This work aims to facilitate a fast magnetic resonance (MR)-only workflow for radiation therapy of intracranial tumors. Here, we evaluate whether synthetic computed tomography (sCT) images generated with a dilated convolutional neural networ...

Creation of knowledge-based planning models intended for large scale distribution: Minimizing the effect of outlier plans.

Journal of applied clinical medical physics
Knowledge-based planning (KBP) can be used to estimate dose-volume histograms (DVHs) of organs at risk (OAR) using models. The task of model creation, however, can result in estimates with differing accuracy; particularly when outlier plans are not p...

Functional-guided radiotherapy using knowledge-based planning.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND AND PURPOSE: There are two significant challenges when implementing functional-guided radiotherapy using 4DCT-ventilation imaging: (1) lack of knowledge of realistic patient specific dosimetric goals for functional lung and (2) ensuring co...

Fully automated searching for the optimal VMAT jaw settings based on Eclipse Scripting Application Programming Interface (ESAPI) and RapidPlan knowledge-based planning.

Journal of applied clinical medical physics
PURPOSE: Eclipse treatment planning system has not been able to optimize the jaw positions for Volumetric Modulated Arc Therapy (VMAT). The arbitrary and planner-dependent jaw placements define the maximum field size within which multi-leaf-collimato...

Impact of database quality in knowledge-based treatment planning for prostate cancer.

Practical radiation oncology
PURPOSE: This article investigates dose-volume prediction improvements in a common knowledge-based planning (KBP) method using a Pareto plan database compared with using a conventional, clinical plan database.

A singular value decomposition linear programming (SVDLP) optimization technique for circular cone based robotic radiotherapy.

Physics in medicine and biology
With robot-controlled linac positioning, robotic radiotherapy systems such as CyberKnife significantly increase freedom of radiation beam placement, but also impose more challenges on treatment plan optimization. The resampling mechanism in the vendo...