AIMC Topic: Radiotherapy Dosage

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MRI-based treatment planning for proton radiotherapy: dosimetric validation of a deep learning-based liver synthetic CT generation method.

Physics in medicine and biology
Magnetic resonance imaging (MRI) has been widely used in combination with computed tomography (CT) radiation therapy because MRI improves the accuracy and reliability of target delineation due to its superior soft tissue contrast over CT. The MRI-onl...

Deep learning derived tumor infiltration maps for personalized target definition in Glioblastoma radiotherapy.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSE: Glioblastoma is routinely treated by concomitant radiochemotherapy. Current target definition guidelines use anatomic MRI (magnetic resonance imaging) scans, taking into account contrast enhancement and the rather unspecific hyperintensity o...

Dosimetric evaluation of synthetic CT for head and neck radiotherapy generated by a patch-based three-dimensional convolutional neural network.

Medical physics
PURPOSE: To develop and evaluate a patch-based convolutional neural network (CNN) to generate synthetic computed tomography (sCT) images for magnetic resonance (MR)-only workflow for radiotherapy of head and neck tumors. A patch-based deep learning m...

Deep Convolution Neural Network (DCNN) Multiplane Approach to Synthetic CT Generation From MR images-Application in Brain Proton Therapy.

International journal of radiation oncology, biology, physics
PURPOSE: The first aim of this work is to present a novel deep convolution neural network (DCNN) multiplane approach and compare it to single-plane prediction of synthetic computed tomography (sCT) by using the real computed tomography (CT) as ground...

Incorporating dosimetric features into the prediction of 3D VMAT dose distributions using deep convolutional neural network.

Physics in medicine and biology
An accurate prediction of achievable dose distribution on a patient specific basis would greatly improve IMRT/VMAT planning in both efficiency and quality. Recently machine learning techniques have been proposed for IMRT dose prediction based on pati...

Three-dimensional dose prediction for lung IMRT patients with deep neural networks: robust learning from heterogeneous beam configurations.

Medical physics
PURPOSE: The use of neural networks to directly predict three-dimensional dose distributions for automatic planning is becoming popular. However, the existing methods use only patient anatomy as input and assume consistent beam configuration for all ...

Dose distribution prediction in isodose feature-preserving voxelization domain using deep convolutional neural network.

Medical physics
PURPOSE: To implement a framework for dose prediction using a deep convolutional neural network (CNN) based on the concept of isodose feature-preserving voxelization (IFPV) in simplifying the representation of the dose distribution.

Intelligent inverse treatment planning via deep reinforcement learning, a proof-of-principle study in high dose-rate brachytherapy for cervical cancer.

Physics in medicine and biology
Inverse treatment planning in radiation therapy is formulated as solving optimization problems. The objective function and constraints consist of multiple terms designed for different clinical and practical considerations. Weighting factors of these ...

Predicting VMAT patient-specific QA results using a support vector classifier trained on treatment plan characteristics and linac QC metrics.

Physics in medicine and biology
The use of treatment plan characteristics to predict patient-specific quality assurance (QA) measurement results has recently been reported as a strategy to help facilitate automated pre-treatment verification workflows or to provide a virtual assess...