AIMC Topic: Retrospective Studies

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The potential role of an expert computer system to augment the opportunistic detection of individuals with familial hypercholesterolaemia from a community laboratory.

Clinica chimica acta; international journal of clinical chemistry
BACKGROUND: Familial hypercholesterolaemia (FH) is the most common monogenic cause of premature atherosclerotic cardiovascular disease (CVD). However, most individuals with FH remain undiagnosed. We sought to determine if an expert system (ES) at a c...

Machine Learning Approach to Optimizing Combined Stimulation and Medication Therapies for Parkinson's Disease.

Brain stimulation
BACKGROUND: Deep brain stimulation (DBS) of the subthalamic region is an established therapy for advanced Parkinson's disease (PD). However, patients often require time-intensive post-operative management to balance their coupled stimulation and medi...

Transoral robotic surgery for the management of head and neck squamous cell carcinoma of unknown primary.

Acta oto-laryngologica
CONCLUSION: The addition of transoral robotic surgery (TORS) in the diagnostic management of patients classified with head and neck squamous cell carcinoma of unknown primary (SCCUP) is promising and appears to improve detection rates of the primary ...

Abdominal Hysterectomy: Reduced Risk of Surgical Site Infection Associated with Robotic and Laparoscopic Technique.

Surgical infections
BACKGROUND: Hysterectomy is one of the most common procedures performed in the United States. New techniques utilizing laparoscopic and robotic technology are becoming increasingly common. It is unknown if these minimally invasive surgical techniques...

Blurring the boundaries between frame-based and frameless stereotaxy: feasibility study for brain biopsies performed with the use of a head-mounted robot.

Journal of neurosurgery
OBJECT: Frame-based stereotactic interventions are considered the gold standard for brain biopsies, but they have limitations with regard to flexibility and patient comfort because of the bulky head ring attached to the patient. Frameless image guida...

Does preoperative diabetes mellitus affect weight loss outcome after biliopancreatic diversion with duodenal switch?

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
BACKGROUND: Preoperative type 2 diabetes mellitus (T2 DM) has previously been reported as an independent predictor for suboptimal (≤40%) weight loss after Roux-en-Y gastric bypass in patients with T2 DM compared with patients who do not have T2 DM. T...

Evaluation of machine learning algorithms for treatment outcome prediction in patients with epilepsy based on structural connectome data.

NeuroImage
The objective of this study is to evaluate machine learning algorithms aimed at predicting surgical treatment outcomes in groups of patients with temporal lobe epilepsy (TLE) using only the structural brain connectome. Specifically, the brain connect...

The rate of mucosal healing by azathioprine therapy and prediction by artificial systems.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
BACKGROUND/AIMS: We aimed to assess the effect of azathioprine on mucosal healing in patients with inflammatory bowel diseases (IBD). Artificial neural networks were applied to IBD data for predicting mucosal remission.