AIMC Topic: ROC Curve
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Construction of a predictive model for relapse of primary autoimmune hemolytic anemia: a retrospective cohort study.
Annals of medicine
May 22, 2025
OBJECTIVES: To develop a machine learning-based model to predict the relapse risk of Primary Autoimmune Haemolytic Anaemia (AIHA) after the last remission.
The Gut Microbiota in Young Adults with High-Functioning Autism Spectrum Disorder and Its Performance as Diagnostic Biomarkers.
Nutrients
May 22, 2025
Diagnosing ASD in adults presents unique challenges, and there are currently no specific biomarkers for this condition. Most existing studies on the gut microbiota in ASD are conducted in children; however, the composition of the gut microbiota in c...
Performance of multimodal prediction models for intracerebral hemorrhage outcomes using real-world data.
International journal of medical informatics
May 21, 2025
BACKGROUND: We aimed to develop and validate multimodal models integrating computed tomography (CT) images, text and tabular clinical data to predict poor functional outcomes and in-hospital mortality in patients with intracerebral hemorrhage (ICH). ...
Metabolic signature of COVID-19 progression: potential prognostic markers for severity and outcome.
Metabolomics : Official journal of the Metabolomic Society
May 21, 2025
INTRODUCTION: There are significant challenges remain in accurately categorizing the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients.
Phase recognition in manual Small-Incision cataract surgery with MS-TCN + + on the novel SICS-105 dataset.
Scientific reports
May 21, 2025
Manual Small-Incision Cataract Surgery (SICS) is a prevalent technique in low- and middle-income countries (LMICs) but understudied with respect to computer assisted surgery. This prospective cross-sectional study introduces the first SICS video data...
Predicting infections with multidrug-resistant organisms (MDROs) in neurocritical care patients with hospital-acquired pneumonia (HAP): development of a novel multivariate prediction model.
Microbiology spectrum
May 15, 2025
Hospital-acquired pneumonia (HAP) is prevalent in the neuro-intensive care unit (NICU), significantly increasing susceptibility to infections with multidrug-resistant organisms (MDROs), which result in high mortality rates and substantial healthcare ...
Development of a chitosanase 3-like protein 1 assay kit and study of its application in patients with hepatocellular carcinoma.
BMC biotechnology
May 12, 2025
OBJECTIVE: The detection kit for plasma Chitinase-3-like Protein 1 was developed using the magnetic bead chemiluminescence method, in order to investigate the diagnostic value of DD, FDP, CHI3L1, AFP-L3 and PIVKA-II in hepatocellular carcinoma.
Investigation of serum neuroserpin levels in pregnant women diagnosed with pre-eclampsia: a prospective case-control study.
BMC pregnancy and childbirth
May 10, 2025
OBJECTIVE: Neuroserpin, a serine protease inhibitor, is recognized for its anti-inflammatory and neuroprotective properties. Given the central role of inflammation and neurological involvement in the pathophysiology of preeclampsia, this study aimed ...
Reduced blood EPAC1 protein levels as a marker of severe coronary artery disease: the role of hypoxic foam cell-transformed smooth muscle cells.
Journal of translational medicine
May 9, 2025
BACKGROUND: Vascular smooth muscle cells loaded with cholesterol (foam-VSMCs) play a crucial role in the progression of human atherosclerosis. Exchange Protein Directly Activated by cAMP 1 (EPAC1) is a critical protein in the regulation of vascular t...
A correlational study of plasma galectin-3 as a potential predictive marker of postoperative delirium in patients with acute aortic dissection.
Scientific reports
May 8, 2025
This study aimed to demonstrate whether plasma galectin-3 could predict the development of postoperative delirium (POD) in patients with acute aortic dissection (AAD). Prospective, observational study. Cardiac surgery intensive care unit. Consecutive...
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