Post-hepatectomy liver failure (PHLF) is a severe complication following liver surgery. We aimed to develop a novel, interpretable machine learning (ML) model to predict PHLF. We enrolled 312 hepatocellular carcinoma (HCC) patients who underwent hepa...
OBJECTIVES: To establish a precise and efficient diagnostic framework for distinguishing medication-related osteonecrosis of the jaw, radiation-induced osteonecrosis of the jaw, and normal bone tissue, thus enhancing clinical decision-making and enab...
Journal of cancer research and therapeutics
May 2, 2025
BACKGROUND: To develop a deep learning radiomics (DLR) model based on contrast-enhanced computed tomography (CECT) to assess the rat sarcoma (RAS) oncogene status and predict targeted therapy response in colorectal cancer liver metastases (CRLM).
Anoikis and immune cell infiltration are pivotal factors in the pathophysiological mechanism of diabetic nephropathy (DN), yet a comprehensive understanding of the mechanism is lacking. This work aimed to pinpoint distinctive anoikis-related genes (A...
PURPOSE: This study is aimed to develop and validate a machine learning model, which combined radiomics and clinical characteristics to predicting the definitive chemoradiotherapy (dCRT) treatment response in esophageal squamous cell carcinoma (ESCC)...
Photodiagnosis and photodynamic therapy
Apr 28, 2025
BACKGROUND: Ocular hypertension (OHT) is the most significant risk factor for glaucoma. We aimed to develop a model for predicting OHT progression to early glaucoma and to identify key predictors.
BACKGROUND: COVID-19 has been linked to acute kidney injury (AKI) and chronic kidney disease (CKD), but machine learning (ML) models predicting these risks post-pandemic have been absent. We aimed to use large electronic health records (EHR) and ML a...
In existing breast cancer prediction research, most models rely solely on a single type of imaging data, which limits their performance. To overcome this limitation, the present study explores breast cancer prediction models based on multimodal medic...
Computer methods and programs in biomedicine
Apr 25, 2025
BACKGROUND: Prolonged mechanical ventilation (PMV) might cause ventilator-associated pneumonia and diaphragmatic injury, and may lead to worsening clinical weaning outcomes. The present study proposes a comprehensive machine learning (ML) framework f...
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