AIMC Topic: ROC Curve

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Gene expression signatures from whole blood predict amyotrophic lateral sclerosis case status and survival.

Nature communications
Amyotrophic lateral sclerosis (ALS) is a rare and fatal neurodegenerative disease with a median survival of only 2 to 4 years from diagnosis. Improved tools are needed to shorten diagnostic delays and improve prognostication to benefit clinical care....

Comparative study of coronary artery disease prediction: conventional QRISK3 versus enhanced machine learning models combined with particle swarm optimisation algorithm.

Open heart
BACKGROUND: Coronary artery disease (CAD) is one of the biggest causes of mortality worldwide. Risk stratification for early detection is essential for the primary prevention of CAD. QRISK3 is known to overestimate future CAD risk in some populations...

Reliable biomarkers for diabetic nephropathy using machine learning-assisted contrast-enhanced ultrasonography and clinical characteristics.

Clinical and experimental medicine
OBJECTIVE: To utilize machine learning techniques to screen contrast-enhanced ultrasound (CEUS) parameters and clinical characteristics, aiming to differentiate diabetic nephropathy (DN) from non-diabetic renal disease (NDRD) in patients with diabeti...

Predictive value of systemic inflammation response index for atherosclerotic cardiovascular disease risk in patients with hypercholesterolemia: a machine learning study with dual-cohort validation.

Lipids in health and disease
BACKGROUND: Residual cardiovascular risk persists in patients with hypercholesterolemia despite lipid-lowering therapy, underscoring the importance of inflammation in ASCVD development. This study evaluated the relationship between Systemic Inflammat...

Multiple polygenic score approach in colorectal cancer risk prediction.

Scientific reports
Recent studies have demonstrated that for various diseases, incorporating polygenic risk scores (PRSs) for other traits and diseases into the PRS-based risk prediction model may improve predictive performance - known as Multiple Polygenic Score (MPS)...

Transparent AI-driven personalized risk prediction system for acute kidney injury after total hip arthroplasty.

Scientific reports
Acute kidney injury is a common and severe complication following total hip arthroplasty, particularly in elderly or high-risk patients with chronic conditions, significantly increasing morbidity and mortality rates. Traditional prediction methods of...

Machine learning-driven risk stratification for distant metastasis in gastric cancer: A comparative study of clinical features and composite indices integrated models.

PloS one
OBJECTIVE: Distant metastasis (DM) of gastric cancer (GC) represents a significant health challenge due to its high mortality rates, necessitating advancements in early detection and management strategies. The objective of this study was to create a ...

Comparing radiomics, deep learning, and fusion models for predicting occult pleural dissemination in patients with non-small cell lung cancer: a retrospective multicenter study.

BMC cancer
BACKGROUND: Occult pleural dissemination (PD) in non-small cell lung cancer (NSCLC) patients is likely to be missed on computed tomography (CT) scans, associated with poor survival, and generally contraindicated for radical surgery. This study aimed ...

A deep learning approach to predict temporal changes of subdural hemorrhage on computed tomography.

Scientific reports
Subdural hemorrhage (SDH) is a critical condition requiring prompt assessment of its progression using computed tomography (CT). This study aimed to develop a deep-learning model to predict temporal changes in SDH by leveraging Hounsfield Units (HU) ...

Investigating the capability of deep learning models to predict age and biological sex from anterior segment ophthalmic imaging: a multi-centre retrospective study.

BMJ open
OBJECTIVE: To assess the capability of a convolutional neural network trained by transfer learning on anterior segment optical coherence tomography (AS-OCT) images, Placido-disk corneal topography images and external photographs to predict age and bi...