AIMC Topic: Sarcoma

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Soft Tissue Sarcoma: Preoperative MRI-Based Radiomics and Machine Learning May Be Accurate Predictors of Histopathologic Grade.

AJR. American journal of roentgenology
The purpose of this study was to assess the value of radiomics features for differentiating soft tissue sarcomas (STSs) of different histopathologic grades. The T1-weighted and fat-suppressed T2-weighted MR images of 70 STSs of varying grades (35 l...

Brain pathology identification using computer aided diagnostic tool: A systematic review.

Computer methods and programs in biomedicine
Computer aided diagnostic (CAD) has become a significant tool in expanding patient quality-of-life by reducing human errors in diagnosis. CAD can expedite decision-making on complex clinical data automatically. Since brain diseases can be fatal, rapi...

Comparison of CT and MRI images for the prediction of soft-tissue sarcoma grading and lung metastasis via a convolutional neural networks model.

Clinical radiology
AIM: To realise the automated prediction of soft-tissue sarcoma (STS) grading and lung metastasis based on computed tomography (CT), T1-weighted (T1W) magnetic resonance imaging (MRI), and fat-suppressed T2-weighted MRI (FST2W) via the convolutional ...

Machine learning analysis of gene expression data reveals novel diagnostic and prognostic biomarkers and identifies therapeutic targets for soft tissue sarcomas.

PLoS computational biology
Based on morphology it is often challenging to distinguish between the many different soft tissue sarcoma subtypes. Moreover, outcome of disease is highly variable even between patients with the same disease. Machine learning on transcriptome sequenc...

Machine Learning to Differentiate T2-Weighted Hyperintense Uterine Leiomyomas from Uterine Sarcomas by Utilizing Multiparametric Magnetic Resonance Quantitative Imaging Features.

Academic radiology
RATIONALE AND OBJECTIVE: Uterine leiomyomas with high signal intensity on T2-weighted imaging (T2WI) can be difficult to distinguish from sarcomas. This study assessed the feasibility of using machine learning to differentiate uterine sarcomas from l...

Unsupervised versus Supervised Identification of Prognostic Factors in Patients with Localized Retroperitoneal Sarcoma: A Data Clustering and Mahalanobis Distance Approach.

BioMed research international
The aim of this report is to unveil specific prognostic factors for retroperitoneal sarcoma (RPS) patients by univariate and multivariate statistical techniques. A phase I-II study on localized RPS treated with high-dose ifosfamide and radiotherapy f...

Treatment-related features improve machine learning prediction of prognosis in soft tissue sarcoma patients.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
BACKGROUND AND PURPOSE: Current prognostic models for soft tissue sarcoma (STS) patients are solely based on staging information. Treatment-related data have not been included to date. Including such information, however, could help to improve these ...

Acute gastrointestinal toxicity and bowel bag dose-volume parameters for preoperative radiation therapy for retroperitoneal sarcoma.

Practical radiation oncology
PURPOSE: Acute gastrointestinal (GI) toxicity has been studied in GI and gynecological (GYN) cancers, with volume receiving 15 Gy (V15) <830 mL, V25 <650 mL, and V45 <195 mL identified as dose constraints for the peritoneal space (bowel bag [BB]). Th...

Machine learning based diagnostics of veterinary cancer on ultrasound and optical imaging data.

The veterinary quarterly
Study advances current diagnostic efficiency of canine/feline (sub-)cutaneous tumors using machine learning and multimodal imaging data. White light (WL), fluorescence (FL) and ultrasound (US) imaging were combined into hybrid approaches to different...