AIMC Topic: Surface Properties

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Inhibition of bacterial surface colonization by immobilized silver nanoparticles depends critically on the planktonic bacterial concentration.

Journal of colloid and interface science
Immobilization of antimicrobial silver nanoparticles (AgNPs) on surfaces has been proposed as a method to inhibit biofouling or as a possible route by which incidental releases of AgNPs may interfere with biofilms in the natural environment or in was...

Preparation of Concentrated Chitosan/DNA Nanoparticle Formulations by Lyophilization for Gene Delivery at Clinically Relevant Dosages.

Journal of pharmaceutical sciences
Chitosan/DNA polyplexes have been optimized for efficient and safe in vitro and in vivo gene delivery. Clinical application of this technology requires the development of formulations with higher concentrations to reach therapeutic dosages. Polyplexe...

Preparation, Characterization, and Antitumor Activities of Miriplatin-Loaded Liposomes.

Journal of pharmaceutical sciences
Because of the insolubility of miriplatin in water, miriplatin and lipiodol suspension is the sole formulation of miriplatin approved in Japan to treat hepatocellular carcinoma by transcatheter arterial chemoembolization. Until now, there have been n...

Microrobotized blasting improves the bone-to-textured implant response. A preclinical in vivo biomechanical study.

Journal of the mechanical behavior of biomedical materials
This study evaluated the effect of microrobotized blasting of titanium endosteal implants relative to their manually blasted counterparts. Two different implant systems were utilized presenting two different implant surfaces. Control surfaces (Manual...

Improvement in Laser-Irradiation Efficiency of Robot-Assisted Laser Hair Removal Through Pose Measurement of Skin Surface.

Photomedicine and laser surgery
OBJECTIVE: This study aims to improve the performance of an automatic laser hair removal (LHR) system by applying an algorithm that considers the curve and slant of the skin surface.

A methodological evaluation and predictive in silico investigation into the multi-functionality of arginine in directly compressed tablets.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
The acceleration of solid dosage form product development can be facilitated by the inclusion of excipients that exhibit poly-/multi-functionality with reduction of the time invested in multiple excipient optimisations. Because active pharmaceutical ...

Surface modeling of workpiece and tool trajectory planning for spray painting robot.

PloS one
Automated tool trajectory planning for spray-painting robots is still a challenging problem, especially for a large free-form surface. A grid approximation of a free-form surface is adopted in CAD modeling in this paper. A free-form surface model is ...

Optimization of controlled release nanoparticle formulation of verapamil hydrochloride using artificial neural networks with genetic algorithm and response surface methodology.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
This study was performed to optimize the formulation of polymer-lipid hybrid nanoparticles (PLN) for the delivery of an ionic water-soluble drug, verapamil hydrochloride (VRP) and to investigate the roles of formulation factors. Modeling and optimiza...

Detection and direct readout of drugs in human urine using dynamic surface-enhanced Raman spectroscopy and support vector machines.

Analytical chemistry
A new, novel, rapid method to detect and direct readout of drugs in human urine has been developed using dynamic surface-enhanced Raman spectroscopy (D-SERS) with portable Raman spectrometer on gold nanorods (GNRs) and a classification algorithm call...