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The Role of GDF-15 in Heart Failure Patients With Chronic Kidney Disease.

The Canadian journal of cardiology
BACKGROUND: Growth differentiation factor-15 (GDF-15) is a stress-inducible cytokine and member of the transforming growth factor-β cytokine superfamily that refines prognostic assessment in subgroups of patients with heart failure (HF). We evaluated...

Heart Sound Segmentation-An Event Detection Approach Using Deep Recurrent Neural Networks.

IEEE transactions on bio-medical engineering
OBJECTIVE: In this paper, we accurately detect the state-sequence first heart sound (S1)-systole-second heart sound (S2)-diastole, i.e., the positions of S1 and S2, in heart sound recordings. We propose an event detection approach without explicitly ...

Machine learning based framework to predict cardiac arrests in a paediatric intensive care unit : Prediction of cardiac arrests.

Journal of clinical monitoring and computing
A cardiac arrest is a life-threatening event, often fatal. Whilst clinicians classify some of the cardiac arrests as potentially predictable, the majority are difficult to identify even in a post-incident analysis. Changes in some patients' physiolog...

Statistical Approaches Based on Deep Learning Regression for Verification of Normality of Blood Pressure Estimates.

Sensors (Basel, Switzerland)
Oscillometric blood pressure (BP) monitors currently estimate a single point but do not identify variations in response to physiological characteristics. In this paper, to analyze BP's normality based on oscillometric measurements, we use statistical...

Using machine learning to characterize heart failure across the scales.

Biomechanics and modeling in mechanobiology
Heart failure is a progressive chronic condition in which the heart undergoes detrimental changes in structure and function across multiple scales in time and space. Multiscale models of cardiac growth can provide a patient-specific window into the p...

Blood Pressure Estimation Using Time Domain Features of Auscultatory Waveforms and Deep Learning.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
This paper presents a novel method to estimate systolic blood pressure (SBP) and diastolic blood pressure (DBP) from time domain features extracted on auscultatory waveforms (AWs) using a long short term memory (LSTM) recurrent neural network (RNN). ...

Detecting liver fibrosis using a machine learning-based approach to the quantification of the heart-induced deformation in tagged MR images.

NMR in biomedicine
Liver disease causes millions of deaths per year worldwide, and approximately half of these cases are due to cirrhosis, which is an advanced stage of liver fibrosis that can be accompanied by liver failure and portal hypertension. Early detection of ...