AIMC Topic: Viral Load
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Hepatitis C viral load and genotypes among Nigerian subjects with chronic infection and implication for patient management: a retrospective review of data.
The Pan African medical journal
Dec 10, 2020
INTRODUCTION: Hepatitis C Virus (HCV) is highly infectious with no currently available vaccine. Prior to treatment, it is recommended to confirm HCV infection with either quantitative or qualitative nucleic acid test. Access to these assays in Nigeri...
A Novel Strategy for the Development of Vaccines for SARS-CoV-2 (COVID-19) and Other Viruses Using AI and Viral Shell Disorder.
Journal of proteome research
Oct 2, 2020
A model that predicts levels of coronavirus (CoV) respiratory and fecal-oral transmission potentials based on the shell disorder has been built using neural network (artificial intelligence, AI) analysis of the percentage of disorder (PID) in the nuc...
Random forest machine learning algorithm predicts virologic outcomes among HIV infected adults in Lausanne, Switzerland using electronically monitored combined antiretroviral treatment adherence.
AIDS care
Apr 8, 2020
Machine Learning (ML) can improve the analysis of complex and interrelated factors that place adherent people at risk of viral rebound. Our aim was to build ML model to predict RNA viral rebound from medication adherence and clinical data. Patients w...
Characterization of low level viraemia in HIV-infected patients receiving boosted protease inhibitor-based antiretroviral regimens.
HIV research & clinical practice
Jan 30, 2020
To understand the pathogenesis of low level viraemia (LLV) in HIV-infected patients on boosted protease inhibitors (PI/b), we enrolled 34 subjects with a median HIV-RNA 79 copies/mL and followed them for 15 months. Samples for next generation sequenc...
Mutation
Humans
Viremia
Female
Anti-Retroviral Agents
High-Throughput Nucleotide Sequencing
gag Gene Products, Human Immunodeficiency Virus
Antiretroviral Therapy, Highly Active
Adult
United Kingdom
HIV-1
Drug Resistance, Multiple, Viral
Male
HIV Protease
Middle Aged
HIV Protease Inhibitors
HIV Infections
Viral Load
Ritonavir-boosted paritaprevir, ombitasvir plus ribavirin could improve eGFR in patients with renal impairment and HCV: an Egyptian cohort.
Expert review of gastroenterology & hepatology
Nov 13, 2018
BACKGROUND: The present study aimed at evaluation of changes in estimated glomerular filtration rate (eGFR) among chronic Hepatitis C virus (HCV) patients with chronic kidney disease (CKD) Stages 3-5 who were treated with 12 weeks of ritonavir-booste...
Renal Insufficiency, Chronic
Treatment Outcome
Glomerular Filtration Rate
Cyclopropanes
Recovery of Function
Egypt
Sulfonamides
Hepacivirus
Proline
Drug Therapy, Combination
Viral Load
Time Factors
Antiviral Agents
Genotype
Kidney
Young Adult
Humans
Hepatitis C, Chronic
Macrocyclic Compounds
Adult
Prospective Studies
Valine
Male
Ribavirin
Female
Anilides
Sustained Virologic Response
Middle Aged
Aged
Carbamates
Renal Dialysis
Lactams, Macrocyclic
A comparative study of logistic regression based machine learning techniques for prediction of early virological suppression in antiretroviral initiating HIV patients.
BMC medical informatics and decision making
Sep 4, 2018
BACKGROUND: Treatment with effective antiretroviral therapy (ART) lowers morbidity and mortality among HIV positive individuals. Effective highly active antiretroviral therapy (HAART) should lead to undetectable viral load within 6 months of initiati...
Urinary exosomal viral microRNA as a marker of BK virus nephropathy in kidney transplant recipients.
PloS one
Dec 21, 2017
OBJECTIVE: Bkv-miR-B1-5p, one of the microRNAs encoded by BK virus, was recently reported to be elevated in the blood among the patients with BK virus nephropathy (BKVN). Urinary exosome was suggested to be a possible source of biomarker for kidney d...
A European multicenter study on the analytical performance of the VERIS HBV assay.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
Dec 19, 2017
BACKGROUND: Hepatitis B viral load monitoring is an essential part of managing patients with chronic Hepatits B infection. Beckman Coulter has developed the VERIS HBV Assay for use on the fully automated Beckman Coulter DxN VERIS Molecular Diagnostic...
Evaluation of a human adenovirus viral load assay using the Altona RealStar® PCR test.
Diagnostic microbiology and infectious disease
Dec 2, 2017
This study evaluated the performance of the Altona Diagnostics RealStar® Adenovirus Research Use Only (RUO) real-time PCR reagents for HAdV quantitation in plasma samples from immunodeficient patients. The assay was linear from 2.30-9.17 log copies/m...
An inactivated influenza D virus vaccine partially protects cattle from respiratory disease caused by homologous challenge.
Veterinary microbiology
Dec 21, 2016
Originally isolated from swine, the proposed influenza D virus has since been shown to be common in cattle. Inoculation of IDV to naïve calves resulted in mild respiratory disease histologically characterized by tracheitis. As several studies have as...
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