AI Medical Compendium Journal:
Journal of translational medicine

Showing 91 to 100 of 102 articles

Purification of viable peripheral blood mononuclear cells for biobanking using a robotized liquid handling workstation.

Journal of translational medicine
BACKGROUND: The purification of peripheral blood mononuclear cells (PBMCs) by means of density gradient (1.07 g/mL) centrifugation is one of the most commonly used methods in diagnostics and research laboratories as well as in biobanks. Here, we eval...

Predictive model for acute respiratory distress syndrome events in ICU patients in China using machine learning algorithms: a secondary analysis of a cohort study.

Journal of translational medicine
BACKGROUND: To develop a machine learning model for predicting acute respiratory distress syndrome (ARDS) events through commonly available parameters, including baseline characteristics and clinical and laboratory parameters.

Personalized prediction of live birth prior to the first in vitro fertilization treatment: a machine learning method.

Journal of translational medicine
BACKGROUND: Infertility has become a global health issue with the number of couples seeking in vitro fertilization (IVF) worldwide continuing to rise. Some couples remain childless after several IVF cycles. Women undergoing IVF face greater risks and...

Discrimination of indoor versus outdoor environmental state with machine learning algorithms in myopia observational studies.

Journal of translational medicine
BACKGROUND: Wearable smart watches provide large amount of real-time data on the environmental state of the users and are useful to determine risk factors for onset and progression of myopia. We aim to evaluate the efficacy of machine learning algori...

MLMDA: a machine learning approach to predict and validate MicroRNA-disease associations by integrating of heterogenous information sources.

Journal of translational medicine
BACKGROUND: Emerging evidences show that microRNA (miRNA) plays an important role in many human complex diseases. However, considering the inherent time-consuming and expensive of traditional in vitro experiments, more and more attention has been pai...

Discriminant analysis and machine learning approach for evaluating and improving the performance of immunohistochemical algorithms for COO classification of DLBCL.

Journal of translational medicine
BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) is classified into germinal center-like (GCB) and non-germinal center-like (non-GCB) cell-of-origin groups, entities driven by different oncogenic pathways with different clinical outcomes. DLBCL clas...

Comparison and development of machine learning tools in the prediction of chronic kidney disease progression.

Journal of translational medicine
BACKGROUND: Urinary protein quantification is critical for assessing the severity of chronic kidney disease (CKD). However, the current procedure for determining the severity of CKD is completed through evaluating 24-h urinary protein, which is incon...

Machine-learned models using hematological inflammation markers in the prediction of short-term acute coronary syndrome outcomes.

Journal of translational medicine
BACKGROUND: Increased systemic and local inflammation play a vital role in the pathophysiology of acute coronary syndrome. This study aimed to assess the usefulness of selected machine learning methods and hematological markers of inflammation in pre...

R-100 improves pulmonary function and systemic fluid balance in sheep with combined smoke-inhalation injury and Pseudomonas aeruginosa sepsis.

Journal of translational medicine
BACKGROUND: Septic shock is a major cause of death in intensive care units around the world . The aim of the study was to investigate whether the novel drug R-100 (a superoxide degradation catalyst and nitric oxide donor) improves pulmonary function ...

Exhaled breath condensate metabolome clusters for endotype discovery in asthma.

Journal of translational medicine
BACKGROUND: Asthma is a complex, heterogeneous disorder with similar presenting symptoms but with varying underlying pathologies. Exhaled breath condensate (EBC) is a relatively unexplored matrix which reflects the signatures of respiratory epitheliu...