AIMC Topic: Adult

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Evaluation of the feasibility of explainable computer-aided detection of cardiomegaly on chest radiographs using deep learning.

Scientific reports
We examined the feasibility of explainable computer-aided detection of cardiomegaly in routine clinical practice using segmentation-based methods. Overall, 793 retrospectively acquired posterior-anterior (PA) chest X-ray images (CXRs) of 793 patients...

Sexing white 2D footprints using convolutional neural networks.

PloS one
Footprints are left, or obtained, in a variety of scenarios from crime scenes to anthropological investigations. Determining the sex of a footprint can be useful in screening such impressions and attempts have been made to do so using single or multi...

Machine learning identifies ICU outcome predictors in a multicenter COVID-19 cohort.

Critical care (London, England)
BACKGROUND: Intensive Care Resources are heavily utilized during the COVID-19 pandemic. However, risk stratification and prediction of SARS-CoV-2 patient clinical outcomes upon ICU admission remain inadequate. This study aimed to develop a machine le...

Identification of biomarkers for acute leukemia via machine learning-based stemness index.

Gene
Traditional methods to understand leukemia stem cell (LSC)'s biological characteristics include constructing LSC-like cells and mouse models by transgenic or knock-in methods. However, there are some potential pitfalls in using this method, such as r...

Multi-muscle deep learning segmentation to automate the quantification of muscle fat infiltration in cervical spine conditions.

Scientific reports
Muscle fat infiltration (MFI) has been widely reported across cervical spine disorders. The quantification of MFI requires time-consuming and rater-dependent manual segmentation techniques. A convolutional neural network (CNN) model was trained to se...

Comparative analysis of machine learning approaches to classify tumor mutation burden in lung adenocarcinoma using histopathology images.

Scientific reports
Both histologic subtypes and tumor mutation burden (TMB) represent important biomarkers in lung cancer, with implications for patient prognosis and treatment decisions. Typically, TMB is evaluated by comprehensive genomic profiling but this requires ...

Natural language processing for prediction of readmission in posterior lumbar fusion patients: which free-text notes have the most utility?

The spine journal : official journal of the North American Spine Society
BACKGROUND CONTEXT: The increasing volume of free-text notes available in electronic health records has created an opportunity for natural language processing (NLP) algorithms to mine this unstructured data in order to detect and predict adverse outc...

Accounting for symptom heterogeneity can improve neuroimaging models of antidepressant response after electroconvulsive therapy.

Human brain mapping
Depression symptom heterogeneity limits the identifiability of treatment-response biomarkers. Whether improvement along dimensions of depressive symptoms relates to separable neural networks remains poorly understood. We build on work describing thre...